Background: Endometriosis is a chronic and debilitating disease, which affects millions of young women worldwide. Although medicine has incontestably evolved in the last years, there is no common ground regarding the early and accurate diagnosis of this condition, its pathogenic mechanisms, and curative treatment. Even though the spontaneous resolution of endometriosis is sometimes possible, recent reports suggested that it can be a progressive condition. It can associate chronic pelvic pain, vaginal bleeding, infertility, or malignant degenerescence. Conventional treatments could produce many side effects, and despite treatment, the symptoms may reappear. In recent years, experimental evidence suggested that plant-based medicine could exert beneficial effects on endometriosis and endometriosis-related symptoms. This study aims to highlight the pharmaceutical activity of phytochemicals and medicinal plants against endometriosis and to provide a source of information regarding the alternative treatment of this condition. Methods: For this review, we performed a research using PubMed, GoogleScholar, and CrossRef databases. We selected the articles published between January 2000 and July 2020, written in English. Results: We found 17 medicinal plants and 13 phytochemicals, which have demonstrated their beneficial effects against endometriosis. Several of their biological activities consist of antiangiogenic, anti-inflammatory effects, and oxidative-stress reduction. Conclusion: Medicinal herbs and their bioactive compounds exhibit antiangiogenic, antioxidant, sedative and pain-alleviating properties and the effects recorded until now encourage their use for the conservative management of endometriosis.

Among congenital malformations of the gastrointestinal tract, the most frequent pathology is the esophageal atresia. The subsequent implications are impairment of physiological processes, such as feeding or swallowing, followed by various complications. We performed a retrospective study for ten years at the Clinical Hospital of Obstetrics and Gynecology "Dr. I.A. Sbârcea" in Braşov. There were registered 42751 newborns, of which 23 have been diagnosed with esophageal atresia. We found that those infants with an antenatal diagnosis and proper pregnancy care were associated with better outcomes. Factors such as the technical advances in ultrasonography and appropriate routine prenatal follow-up during pregnancy have a potentially significant influence on the prognosis of these patients.

Depression has a high incidence among perimenopausal women. This systematic review focuses on the connection between hormonal fluctuations and depressive symptoms. The 5% chances of depression are correlated with increasing additional year between menarche and menstrual transition (MT) onset. The higher rates of depressive symptoms were associated with more substantial variation in serum estradiol. Progesterone > 6 ng / dL has been linked with lower rates of depressive symptoms. The results may also indicate an interaction of ovarian hormones, serotonin deficiency and cortisol in this process.