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E vidence-based nursing practice involves integration of a problem-solving approach within the context of caring, considering best evidence from studies, patient care data, clinical experience and expertise, and patients' preferences and values.1 Health care agencies, government agencies, and national professional organizations such as the American Association of Critical-Care Nurses have all been supporters of evidence-based practice (EBP) as studies continue to show improved outcomes when best evidence is used in the delivery of patient care. Feature Evidence-based nursing practice is essential to the delivery of high-quality care that optimizes patients' outcomes. Studies continue to show improved outcomes when best evidence is used in the delivery of patient care. Despite awareness of the importance of practicing by using best evidence, achieving and sustaining evidencebased practice within practice environments can be challenging, and research suggests that integration of evidence-based practice into daily clinical practice remains inconsistent. This article addresses 4 practice issues that, first, are within the realm of nursing and if changed might improve care of patients and, second, are areas in which the tradition and the evidence do not agree and practice continues to follow tradition. The topics addressed are (1) noninvasive measurement of blood pressure in children, (2) oxygen administration for patients with chronic obstructive pulmonary disease, (3) intravenous catheter size and blood administration, and (4) infection control practices to prevent infections. The related beliefs, current evidence, and recommendations for practice related to each topic are described. (Critical Care Nurse. 2013;33[2]:28-44) This article has been designated for CNE credit. A closed-book, multiple-choice examination follows this article, which tests your knowledge of the following objectives:1. Identify key evidence-based components that demonstrate how research can be translated into bedside nursing practice 2. Analyze 4 nursing practice issues to understand how to incorporate evidence-based guidelines into nursing interventions 3. Validate evidence-based guidelines and nursing research to incorporate practice changes in your own work environment

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