We observed the effect of the 5-hydroxytryptamine synthesis inhibitor p-chlorophenylalanine on aggression in male firemouth cichlids (Cichlasoma meeki). p-Chlorophenylalanine-treated firemouths showed a significantly greater number of mirror-directed bites as compared with saline-injected controls. This finding is consistent with the effects of this drug on social aggression in mammals and birds and supplements previous reports that 5-hydroxytryptamine inhibits aggression in fish.

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