No abstract

Face recognition is an extensively research topic in pattern recognition and image processing fields due to its broad application prospects in many areas such as counter terrorism, access identification, electronic passport, e-government affairs, etc. Inspired by the Gabor phase information and local image information content, a novel face description algorithm using adaptive Local Weighted Gabor Comprehensive Histogram (LWGCH) is proposed. It consists of two components: Local Gabor Comprehensive Histogram (LGCH) and Contribution Map (CM). Actually, the adaptive local weighted Gabor comprehensive histogram is generated with LGCH weighed by CM calculated by information content model. Finally, Extensive experiments on ORL, YALE, CMUPIE and Yale B face databases validate the effectiveness of the proposed methods under various conditions of partial occlusion, complex illumination, different expressions and poses. Experimental results indicate that the proposed algorithm is a competitive and robust method compared with several state-of-the-art approaches.

Some food-derived bioactive peptides exhibit prominent immunoregulatory activity. We previously demonstrated that the rice-derived PEP1 peptide, GIAASPFLQSAAFQLR, has strong immunological activity. However, the mechanism of this action is still unclear. In the present study, full-length transcripts of mouse dendritic cells (DC2.4) treated with PEP1 were sequenced using the PacBio sequencing platform, and the transcriptomes were compared via RNA sequencing (RNA-Seq). The characteristic markers of mature DCs, the cluster of differentiation CD86, and the major histocompatibility complex (MHC-II), were significantly upregulated after the PEP1 treatment. The molecular docking suggested that hydrogen bonding and electrostatic interactions played important roles in the binding between PEP1, MHC-II, and the T-cell receptor (TCR). In addition, the PEP1 peptide increased the release of anti-inflammatory factors (interleukin-4 and interleukin-10) and decreased the release of pro-inflammatory factors (interleukin-6 and tumor necrosis factor-α). Furthermore, the RNA-seq results showed the expression of genes involved in several signaling pathways, such as the NF-κB, MAPK, JAK-STAT, and TGF-β pathways, were regulated by the PEP1 treatment, and the changes confirmed the immunomodulatory effect of PEP1 on DC2.4 cells. This findings revealed that the PEP1 peptide, derived from the byproduct of rice processing, is a potential natural immunoregulatory alternative for the treatment of inflammation.