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round blue‐staining bodies in the cytoplasm of neutrophil leucocytes were reported by Döhle in 1911. He observed these inclusion bodies (now known as Döhle bodies) in scarlet fever, but similar structures have been noted on numerous occasions since, in association with various different diseases including diphtheria (Kolmer, 1912), typhus (MacEwen, 1914), tuberculosis (Bachman and Lucke, 1918) and in patients with burns (Weiner and Topley, 1955). May (1909) noticed persistent inclusion bodies in the neutrophils of a healthy person, in association with giant platelets. It was not until 1945 that this association was shown in some cases to be familial, when Hegglin (1945) reported a family with Döhle bodies in their neutrophils and chronic thrombocytopenia. More recently, Petz, Smith and Nelson (1960), Wassmuth, De Groote, Hamilton and Sheets (1961), Oski, Naiman, Allen and Diamond (1962) and Buchanan, Pearce and Wetherley‐Mein (1964) have reported families with the May‐Hegglin anomaly. We have been unable to find any report of Döhle bodies associated with transient thrombocytopenia. Most reports of transient Döhle bodies have referred to their presence in certain specific conditions. Random observations in this department suggested that they occurred more frequently, and were found in a wider range of conditions, than might be supposed from a study of the literature. A moderate thrombocytopenia was also noted on several occasions to be associated with the presence of transient Döhle bodies. The results of a formal investigation into the incidence and nature of these structures, as well as their association with thrombocytopenia, is reported here.

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A 66-year-old female presented to casualty with recurrent syncopal episodes and a history of ischaemic heart disease. Initial investigations did not provide a definitive diagnosis. Subsequent CT scanning identified a giant pseudoaneurysm of the left anterior descending coronary artery, which is the largest reported to date. We include a short discussion on current literature surrounding coronary artery pseudoaneurysmal disease.