Background:Amlapitta is a commonly encountered disease of Annavaha Srotasa (gastrointestinal system) described in various classical Ayurvedic texts. The cardinal features of Amlapitta are Avipaka (indigestion), Hritkantha Daha (heart and throat burn) and Tikta-Amlodgara (sour and bitter belching). This disease can be correlated with gastroesophageal reflux disease based on the clinical features. Baladi Manduram is one of the unique formulations mentioned in Rasa Kamadhenu indicated for the management of Amlapitta.Aims:This study is aimed to evaluate the efficacy of Baladi Manduram in the management of Amlapitta.Materials and Methods:A non-randomized, single-armed, open-labeled clinical trial was conducted in thirty patients having classical symptoms of Amlapitta, administered with 500 mg of Baladi Manduram twice a day after meals for 30 days. The assessment was done based on subjective parameters, i.e., Amlodgara (sour belching), Daha (heart burn), Gaurava (heaviness), Utklesha (nausea), Avipaka (indigestion) and Kshudha Alpata (loss of appetite). The results were statistically analyzed using the paired t-test.Results:Statistically highly significant relief (P < 0.001) was noted in Amlodgara, Hritkantha Daha, Utklesha and Agnimandya and statistically highly significant relief (P < 0.01) was seen in Gaurava and Avipaka.Conclusion:Baladi Manduram can be considered as an effective formulation in the management of Amlapitta.

Rasa oushadies are the potent Ayurvedic preparations mainly containing metals and minerals. These oushadies possess a wide range of therapeutic efficacy and are considered superior because of their qualities like small dose, quick action, palatability and longer shelf life. Tamra Yoga is an important Rasa oushadi described in Rasa Tantra Sara Va Siddha Prayoga Sangraha indicated for the management of the disease Vataja Shula, Gulma and Ajirna. The ingredients present in the "Tamra Yoga" are Tamra Bhasma, Yashtimadhu, Trikatu, Souvarchala Lavana, Chincha Kshara and Bharjitha Hingu. The main pharmaceutical procedures involved in the preparation of Tamra Yoga are Shodhana, Bhavana, Marana, Amrutikarana, Chincha Kshara nirmana, Hingubharjana, Churna nirmana and preparation of capsules of Tamra Yoga. The specific pharmaceutical blend of these contents can result in a more effective formulation. Till date, no research work has been carried out to standardize this formulation. Therefore the present study has been planned to standardize the method of preparation of Tamra Yoga according to the method explained in the classical literature.

Switra can be compared with Vitiligo of contemporary science. Switra is a pigmentary disorder of great socio-medical importance and defined as, acquired, idiopathic, hypo melanosis of skin and hair. Aims and objectives: Therapeutic evaluation of Switrahara Churna on Switra. Materials and Methods: In present study, total 32 patients with signs and symptoms of Switra were selected from the OPD, Rasa Shastra and Bhaishjya Kalpana of S.V Ayurvedic hospital T.T.D Tirupati. Out of them 30 patients completed the course of treatment. Follow up was done every 15th day. The assessment criteria were Twak Swetata, Twak Rukshta, Kandu Daha Twak, Vivarnata and margins. Statistical analysis was carried out using “Analysis tool pack add-in of Microsoft Excel- 2019” and “Graph pad Prism Version- 7” by applying paired ‘t’- Test. Results: Among 30 patients, 18 patients (60%) had moderate improvement, 11 patients (36%) had marked improvement, 1 patient (3.33%) had mild improvement. Conclusion: The therapy in the form of Lepa i.e., Switrahara Churna is a safe and effective in the management of Switra.

Objective: Baladi Manduram (BM) is one of the most important and potent herbo-mineral formulation described in Ayurvedic classics viz., Rasa Kamadhenu and Rasayoga sagara specified for the management of the disease Amlapitta. BM contains

Rasa Shastra is the pharmaceutical branch of Ayurveda. As like any other medical system, success of Ayurvedic treatment also depends upon quality of medicine prescribed to the patient. The integral part of Rasa Shastra lies in the successful pharmaceutical process. Rasa oushadis are the potent Ayurvedic preparations mainly containing metals and minerals. These oushadis possess a wide range of therapeutic efficacy and are considered superior because of their qualities like small dose, quick action, palatability and longer shelf life. Mayaphaladi Churna is an important Rasa oushadi described in Rasa Tantra Sara Va Siddha Prayoga Sangraha- Part 2, Streerogadhikara indicated for the management of the diseases Swetapradara and Yonibramsha. The ingredients present in the ‘Mayaphaladi Churna’ are Kukkutanda twak bhasma (Egg Shell Ash), Shuddha Sphatika (Alum), Mayaphala Churna (Quercus Infectoria Oliv.), Amalaki Churna (Emblica Officinalis Gearth), Ashwagandha Churna (Withania Somnifera Linn.) and Sita Churna (Sugar Candy). The main pharmaceutical procedures involved in the preparation of Mayaphaladi Churna are Shodhana, Marana, Churna nirmana and preparation of Mayaphaladi Churna. The specific pharmaceutical blend of these contents can result in a more effective formulation. Therefore the present study has been planned to standardize the method of preparation of Mayaphaladi Churna according to the method explained in the classical literatures. Keywords: Mayaphaladi Churna, Shodhana, Marana, Churna Nirmana, Standardization.