Central giant cell granuloma formerly called as giant cell reparative granuloma is a non neoplastic proliferative lesion of unknown etiology. It occurs most commonly in mandible, but can also occur in maxilla. The case described here involved maxilla which was treated with surgical excision.
INTRODUCTIONTumours of salivary glands are rare constituting less than one percent of all tumours and 3% to 10% of the neoplasms of head and neck region.1,2 They are a heterogeneous group of tumours and present distinct clinicopathological features. Parotid gland accounts for 80% of salivary gland tumors followed by submandibular gland (10-15%).3 Majority of the primary tumours of salivary glands are benign but diagnosis of malignant tumours pose many difficulties in routine practice due to a wide spectrum of entities with overlapping in morphology.The histopathological features are intricate and differences between different types are very subtle and as such many challenges are encountered in establishing histological diagnosis, classification and grading of salivary gland neoplasms. The present work is taken up to study the incidence of salivary gland tumours in our ABSTRACT Background: Tumours of salivary glands are rare neoplasms of head and neck region accounting for less than one percent of all tumours. Parotid gland accounts for majority of tumors followed by submandibular gland. As such many challenges are encountered in establishing histological diagnosis, classification, grading and management of salivary gland neoplasms. This study is taken up to study the incidence of salivary gland tumours in our institution and analyse histological criteria for diagnosis and grading systems in vogue for common malignant lesions.
Aim: Follicular variant of papillary thyroid carcinoma [FVPC] as a diagnostic entity has been beset by many controversies. In this study, we describe the nuclear features essential for the diagnosis and analyze the difficulties that confront pathologists as it is important to avoid pitfalls because appropriate management protocol depends upon on an accurate diagnosis of this variant. Materials and Methods: A total of 30 cases, diagnosed as FVPC over a period of two years in the Department of Pathology, were taken for the study. Haematoxylin and Eosin stained sections were reviewed. The extent and distribution of nuclear features were analyzed. Results: The 30 cases of FVPC were categorized into encapsulated and infiltrative groups basing on the presence or lack of capsule and capsular invasion and vascular invasion. Conclusion: FVPC is diagnosed basing on specific nuclear features and hence histopathology still remains the gold standard for the accurate diagnosis.
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