Being a prevalent form of social communications on the Internet, billions of short texts are generated everyday. Discovering knowledge from them has gained a lot of interest from both industry and academia. The short texts have a limited contextual information, and they are sparse, noisy and ambiguous, and hence, automatically learning topics from them remains an important challenge. To tackle this problem, in this paper, we propose a semantics-assisted non-negative matrix factorization (SeaNMF) model to discover topics for the short texts. It effectively incorporates the word-context semantic correlations into the model, where the semantic relationships between the words and their contexts are learned from the skip-gram view of the corpus. The SeaNMF model is solved using a block coordinate descent algorithm. We also develop a sparse variant of the SeaNMF model which can achieve a better model interpretability. Extensive quantitative evaluations on various realworld short text datasets demonstrate the superior performance of the proposed models over several other state-of-the-art methods in terms of topic coherence and classification accuracy. The qualitative semantic analysis demonstrates the interpretability of our models by discovering meaningful and consistent topics. With a simple formulation and the superior performance, SeaNMF can be an effective standard topic model for short texts.

Quantitative microscopy and digital image analysis are underutilized in microbial ecology largely because of the laborious task to segment foreground object pixels from background, especially in complex color micrographs of environmental samples. In this paper, we describe an improved computing technology developed to alleviate this limitation. The system's uniqueness is its ability to edit digital images accurately when presented with the difficult yet commonplace challenge of removing background pixels whose three-dimensional color space overlaps the range that defines foreground objects. Image segmentation is accomplished by utilizing algorithms that address color and spatial relationships of user-selected foreground object pixels. Performance of the color segmentation algorithm evaluated on 26 complex micrographs at single pixel resolution had an overall pixel classification accuracy of 99+%. Several applications illustrate how this improved computing technology can successfully resolve numerous challenges of complex color segmentation in order to produce images from which quantitative information can be accurately extracted, thereby gain new perspectives on the in situ ecology of microorganisms. Examples include improvements in the quantitative analysis of (1) microbial abundance and phylotype diversity of single cells classified by their discriminating color within heterogeneous communities, (2) cell viability, (3) spatial relationships and intensity of bacterial gene expression involved in cellular communication between individual cells within rhizoplane biofilms, and (4) biofilm ecophysiology based on ribotype-differentiated radioactive substrate utilization. The stand-alone executable file plus user manual and tutorial images for this color segmentation computing application are freely available at http://cme.msu.edu/cmeias/ . This improved computing technology opens new opportunities of imaging applications where discriminating colors really matter most, thereby strengthening quantitative microscopy-based approaches to advance microbial ecology in situ at individual single-cell resolution.

No abstract

The number of no-shows has a significant impact on the revenue, cost and resource utilization for almost all healthcare systems. In this study we develop a hybrid probabilistic model based on logistic regression and empirical Bayesian inference to predict the probability of no-shows in real time using both general patient social and demographic information and individual clinical appointments attendance records. The model also considers the effect of appointment date and clinic type. The effectiveness of the proposed approach is validated based on a patient dataset from a VA medical center. Such an accurate prediction model can be used to enable a precise selective overbooking strategy to reduce the negative effect of no-shows and to fill appointment slots while maintaining short wait times.