BACKGROUND Laryngeal cancer is the eleventh most common cancer in men worldwide, but is relatively uncommon in women. Cancer larynx constitutes 2.63% of all body cancers in India. Tobacco smoking and alcohol are the major risk factors for laryngeal cancer. The presenting complaints of laryngeal cancer are hoarseness, dysphagia and referred pain in the ear or mass of lymph nodes in the neck. Objectives-1. To describe sociodemographic factors among patients with carcinoma larynx. 2. To assess the spectrum of clinical features in patients with laryngeal carcinoma. 3. To determine the histopathological pattern in carcinoma larynx patients.
MATERIALS AND METHODSA descriptive study was undertaken in ENT Department of Gandhi Hospital and MNJ Cancer Institute, which are tertiary care centres in Hyderabad, Telangana for a period of 2 years (November 2014 -October 2016). Fifty patients who were clinically diagnosed as carcinoma larynx were included in the study. Ethical clearance was obtained from institutional ethics committee. Informed consent was obtained from the patients before including them in the study.
RESULTSThe maximum incidence of carcinoma larynx in this study was found in the age group of 41-60 years (52%) followed by the 61-80 years age group (42%). Around 94% of Cases were male. Almost 96% of patients belonged to low socioeconomic status. Chief complaint noted in this study was change in voice -48%. Alcohol consumption and beedi smoking were found to be the contributing factors in the occurrence of carcinoma larynx.
CONCLUSIONAround 98% of cases showed squamous cell carcinoma on histopathological examination. The most common site of carcinoma larynx was glottis (54%) followed by supraglottis region (44%).
<p class="abstract"><strong>Background:</strong> Globally head and neck cancers constitute amongst 10 most common cancers. In Asia especially in India, global head and neck cancers account to 57.5%.However the true incidence of head and neck cancers in India is hidden suggesting it as ‘tip of iceberg’. India is regarded as having the greatest risk of cancer burden, the reason being population overgrowth. India being the country of diversity, varied cultures and traditions, the demographic characteristic of these cancers also vary in different individuals.</p><p class="abstract"><strong>Methods:</strong> All patients diagnosed with head and neck malignancy after histological confirmation between August 2014 and July 2018 were selected from hospital records. Data regarding age, gender, risk factors, socio economic status, clinical features, staging were taken and statistical analysis was done. </p><p class="abstract"><strong>Results:</strong> A total of 269 cases were collected out of which, 77% of all malignances in males and 23% in females. Squamous cell carcinoma was the most common histological type (94%). Maximum Incidence of HNC (51.6%) was in 40-60 yrs of age. Tobacco was most prevalent risk factor: 58.36% patients present at early stage, 41.63% present at late stage.</p><p class="abstract"><strong>Conclusions:</strong> Oral cancers were most common among all. There is male predominance. Tobacco is the most common modifiable risk factor and most patients presenting at an early stage.</p>
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