Background: Pilonidal sinus disease (PNS) is a chronic inflammatory disease of the natal cleft occurring in young adults. We report our experience with laser hair removal using Nd: YAG laser and IPL for the treatment of pilonidal cysts. Materials and Methods: Twelve patients presenting with pilonidal disease with or without a history of surgery were examined and treated from October 2016 to October 2021. All patients had modifiable risk factors. Treatments were performed with intense pulsed light (IPL) in nine patients and Nd: YAG laser at a wavelength of 1064 nm in five patients, and occasionally both were used in two patients. The number of treatments ranged from three to five, performed at four-to-eight-week intervals. Results: Progressive hair depilation of the gluteal cleft was achieved in all patients. None of the patients have required further surgical treatments to date. No side effects were reported. All patients experienced a partial or complete remission of the pilonidal disease. Conclusion: Laser hair depilation is a promising therapy in the prevention and management of pilonidal disease.

Pruritic papular eruption (PPE) described in HIV is a skin disease often encountered in HIV-positive patients. It is most often a sign of severe immunodeficiency and is commonly reported in African, Southeast Asian, and Indian populations [1,2]. It affects both adult females and males and may also be seen in children. The elementary lesion is a discrete, firm, erythematous, urticarial, very itchy papule of the extremities, face, and trunk, sparing the palms and soles. Painful excoriations in the genital mucosa are sometimes described. The CD4+ lymphocyte count (CD4) is usually below 250 cells/mm3. Histopathology reveals a lymphohistiocytic, inflammatory, perivascular, and periannexal infiltrate with a variable number of eosinophils. According to the World Health Organization (WHO), it is recommended to all HIV patients with antiretroviral therapy (ART), regardless of the staging and the CD4 count [3]. However, an elective treatment for PPE has not yet been found. Regression has been noted in some cases after the initiation of antiretroviral therapy. UVB therapy seems to be the most successful method in cases not improving with antiretroviral therapy [4]. Herein, we report the case of a patient who presented with PPE revealing HIV.

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