Study objective The impairment of the ovarian response in in vitro fertilization (IVF) cycles after salpingectomy remains contentious. Therefore, we investigated whether a history of salpingectomy affects the number of oocytes retrieved in women undergoing IVF in comparison with the number in women without underlying tubal disease. Design Case–control study (Canadian Task Force Classification II-2). Setting A tertiary hospital–affiliated fertility center. Patients Fifty-four women aged <35 years with a history of salpingectomy and 59 age-matched women without tubal disease. Interventions Gonadotropin-releasing hormone antagonist protocol for controlled ovarian stimulation and transvaginal oocyte retrieval. Measurements and main results The antral follicle count (AFC), anti-Müllerian hormone (AMH) levels, and the number of retrieved oocytes were significantly lower in women with prior salpingectomy than in women without tubal disease. Day-3 follicle-stimulating hormone (FSH) levels, total gonadotropin dosage, and stimulation days did not significantly differ between the groups. The indications of salpingectomy (i.e., hydrosalpinx and ectopic pregnancy) did not differ significantly in terms of ovarian response or reserve among women with salpingectomy history. A history of salpingectomy and other factors related to ovarian response in IVF, such as age, AMH, AFC, day-3 FSH, and total gonadotropin dose, were significantly correlated with the number of oocytes retrieved by univariate regression analysis. In the multivariate-adjusted model after controlling all the above-mentioned variables, only AFC and AMH levels continued to exhibit significant associations with the number of retrieved oocytes. In a subgroup analysis, the negative impact of prior salpingectomy on the number of retrieved oocytes was especially significant in women with suboptimal ovarian reserves (defined as AMH < 4 ng/mL), regardless of the indication of salpingectomy or whether salpingectomy was bilateral or unilateral. Conclusion A negative effect on the number of retrieved oocytes in the subsequent IVF cycle after salpingectomy is more likely in women aged <35 years with suboptimal ovarian reserve. Nevertheless, postsurgical AMH and AFC levels still possess a more direct predictive value on ovarian response than the history of salpingectomy.
The potential effect of a typhoon track on the extent of damage makes the track a critical factor during the emergency response phase. Historical typhoon data may provide information for decision makers to anticipate the impact of an upcoming typhoon and develop prevention strategies to reduce the damage. In our preliminary work, we proposed a track similarity algorithm and implemented a real-time search engine for past typhoon events. However, the proposed algorithm was not discussed thoroughly in the preliminary work, and the great number of historical typhoon track records slowed down the similarity calculations. In addition, the tool did not feature the option of automatically importing upcoming typhoon track predictions. This research introduces the assumption of the recentness dominance principle (RDP), explores the details of the track similarity algorithm of the preliminary work, completes the discussion of parameter setting, and developed a method to improve the efficiency of the similarity calculation. In this research, we implemented the proposed advanced methodology by developing a new information display panel featuring the ability to auto-import forecast data. The results of this study provide decision makers and the public with a concise and handy search engine for searching similar historical typhoon records.
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