Background: Spinal anesthesia is commonly administered intraoperatively. However, relative short duration of action is associated with local anesthetics. A variety of adjuvants is used for prolongation of postoperative analgesia. Aims and Objectives: Comparative analysis of intravenous dexmedetomidine as a premedication and spinal anesthesia treatment with intrathecal isobaric ropivacain of 0.75% in elective lower limb surgery and lower abdominal surgery. Material and Methods: Following approval by the ethical committee, 60 patients scheduled for elective lower limb orthopedic surgery and lower abdominal surgery were chosen and randomized into two groups (n=30). The patient was then intrathecally administered 3 ml amount of 0.75 percent isobaric ropivacaine in lateral location. Another syringe containing dexmedetomidine was given after 10 minutes of placement, for 10 minutes using syringe pump. Comparison of sensory block initiation, analgesic effects and hemodynamic effects was made between the 2 classes. Results: Comparison of age distribution of (P=0.164) was not statistically important. In Group P, the median age was (40.96 ± 15.3 years) and in Group S (44.33 ± 12.66 years).
BACKGROUND Dexamethasone (DES) is a very potent anti-inflammatory and analgesic glucocorticoid with very strong activity. The current study is randomised to determine the onset time, duration, and analgesic potency of bupivacaine (BUC) 0.5 percent, relative to BUC 0.5 percent and DES 8 mg by supraclavicular approach for brachial plexus block. METHODS In patients posted for upper limb surgery under a supraclavicular block, a prospective, randomised, double-blinded study was conducted. 60 Class I and II American Society of Anesthesiologists (ASA) patients were randomly divided into two classes. Group A received 0.5 percent of 30 ml BUS and group B received 0.5 percent of 28 ml BUS and 8 mg of 2 ml DES combined. For a single shot blockade of the supraclavicular brachial plexus, 30 ml of a solution was required. RESULTS The mean age of patients who received BUS was 36.9 ± 10.4 years and those who received BUS + DES was 34.7 ± 7.1 years (P = 0.328), there was no statistically significant difference between the mean ages of two groups (P > 0.05). The mean time of onset of sensory block in the BUS group was 8.6 ± 1.2 minutes and 5.6 ± 0.7 minutes in the BUS + DES group. There was a statistically significant difference between the onset of motor block in minutes among BUS and BUS + DES groups, there was a statistically significant difference between the mean ages of the two groups (P < 0.001). There was no statistically meaningful difference between the BUS and BUS + DES classes at various time intervals in the mean heart rate, difference in systolic blood pressure and diastolic blood pressure, and oxygen saturation. CONCLUSIONS The start of sensory and motor blockade also prolongs the length of DES 8 mg to BUS 0.5 percent speeds, thereby supplying improved analgesia and reducing the rescue analgesic requirements. KEYWORDS Bupivacaine, Dexamethasone, Brachial Plexus, Supraclavicular, Sensory Block
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