Background: Several reports have raised the possibility that newly addressed lipid measures might be superior to the traditional ones for cardiovascular risk prediction. However, data on the associations between these lipid measures with metabolic syndrome (MetS) is limited. Methods and Results:A cross-sectional study of participants in routine health examinations was performed. The associations between lipid measure variables (total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), TC/HDL-C, LDL-C/HDL-C, TG/HDL-C ratio and non-HDL-C) and MetS, insulin resistance (IR) by homeostatic model assessment (HOMA) and adiponectin were analyzed in 6,546 participants (3,820 men; mean age 46.0±9.2 years in men, 44.6±9.5 years in women). In multivariable adjusted regression analysis, the 3 lipid ratios of TC/HDL-C, LDL-C/HDL-C and TG/HDL-C showed significant association with the number of MetS components, HOMA and log adiponectin level in both men and women without MetS (P<0.001, respectively), though these relations were weaker in participants with MetS. The mean levels of the lipid ratios also associated with increasing numbers of the MetS components, quartiles of HOMA and adiponectin.Conclusions: Lipid ratios of TC/HDL-C, LDL-C/HDL-C and TG/HDL-C, as well as TG and HDL, were consistently associated with MetS and IR in participants without MetS. Lipid ratios might be used as integrated and simple lipid measures. (Circ J 2010; 74: 931 - 937)

This study indicates that Cerebrolysin is a safe drug that improves the cognitive deficits and global function in patients with mild to moderate AD. Long-term efficacy and safety of Cerebrolysin in Alzheimer's patients should be evaluated in the future.

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This is an open access article distributed under the term s of the Creative Com m ons Attribution N on-Com m ercial License (http://creativecom m ons.org/ licenses/by-nc/4.0) which perm its unrestricted non-com m ercial use, distribution, and reproduction in any m edium , provided the original w ork is properly cited.Background: White blood cell (WBC) counts have been associated with inflammatory condition. Recently, several studies have shown that increased WBC counts have been associated with different components of metabolic syndrome (MS). Therefore, this study was attempted to illustrate the relationship between WBC counts and the MS in Korean.Methods: Among the subjects who visited a health promotion center of an University hospital from February 2010 to February 2011, a total of 6,465 adults were examined. Among them, we excluded those who did not have records of blood test results and questionnaire, acute ill patients, finally 6,459 adults were examined. The MS was defined according to both NCEP ATP III and WHO Asia-Western Pacific criteria. Logistic regression analysis was used to evaluate the correlation between WBC counts and the MS with an adjustment for age and smoking. Results:In the highest quartile of WBC, the odds ratio for MS was 3.63, which showed approximately a three fold increase compared to the lowest quartile. The relative risks for the presence of ≥1, ≥2, ≥3, ≥4 features of the MS also increased as WBC counts increased.Conclusion: WBC counts are associated with the different components and cluster of MS. Thus, WBC counts may also be another feature of MS.

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