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Completing a commonly used repeated sprint protocol with the upper and lower body results in comparable normalized physiological and perceptual responses.

This is the first demonstration of interhemispheric inhibition (IHI) during a locomotor output, arm cycling. IHI was quantified by assessing the depth of the ipsilateral silent period (iSP) evoked via transcranial magnetic stimulation (TMS) of the motor cortex. There was a significant reduction in EMG amplitude of the iSP during cycling compared to the control EMG (16.8 ± 17.1%; p<0.001). Depth and area for measuring the iSP during arm cycling are discussed. NOVELTY • First study to demonstrate activation of the cortical circuit, interhemispheric inhibition, during a locomotor output.

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