The epoxyquinol natural product (+)‐isoepiepoformin (1) has been synthesized for the first time and in an unambiguous fashion by using the scalemic cis‐1,2‐dihydrocatechol 2 as starting material. The spectroscopic data derived from the synthetic sample of compound 1 match those reported in the literature for the natural product and thereby confirm the structure assigned to the latter.
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