Recent developments in capillary electrophoresis with fluorescence detection are reviewed. Instrumental advances have led to increased sensitivity and, therefore, a growing number of applications. Capillary electrophoresis has been coupled with various techniques to achieve multi-dimensional separations. Other advances have focused on temporal resolution when sampling from biological environments, increased sample throughput especially for DNA analysis, and fast separation times. New technologies including chip and channel electrophoretic separations with fluorescence detection are also discussed.

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By varying the conditions of an electrodeposition solution containing phenol and 2-allylphenol, thin poly(oxypheny1ene) films can be formed. These films have been used to insulate flame-etched carbon fiber electrodes to produce smaller electrode tip diameters. Experiments have been performed to test both the insulating properties and the film thickness of this poly(oxypheny1ene) copolymer at pH 5.0,7.0, and 9.0. The effects of monomer concentration on the polymer insulation integrity and film thickness have also been investigated. These experiments show that a decrease in pH results in thinner insulating films. It is also shown that monomer concentration can be decreased to 12mM phenoV18mM 2-allylphenol without causing an appreciable change in the insulating properties of the copolymer film; however, as the concentration is decreased, the pH appears to have less influence on the copolymer thickness.

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