Objective
Our goal is to develop an interface that integrates chronic monitoring of lower urinary tract (LUT) activity with stimulation of peripheral pathways.
Approach
Penetrating microelectrodes were implanted in sacral dorsal root ganglia (DRG) of adult male felines. Peripheral electrodes were placed on or in the pudendal nerve, bladder neck and near the external urethral sphincter. Supra-pubic bladder catheters were implanted for saline infusion and pressure monitoring. Electrode and catheter leads were enclosed in an external housing on the back. Neural signals from microelectrodes and bladder pressure of sedated or awake-behaving felines were recorded under various test conditions in weekly sessions. Electrodes were also stimulated to drive activity.
Main results
LUT single- and multi-unit activity was recorded for 4 to 11 weeks in four felines. As many as 18 unique bladder pressure single-units were identified in each experiment. Some channels consistently recorded bladder afferent activity for up to 41 days, and we tracked individual single-units for up to 23 days continuously. Distension-evoked and stimulation-driven (DRG and pudendal) bladder emptying was observed, during which LUT sensory activity was recorded.
Significance
This chronic implant animal model allows for behavioral studies of LUT neurophysiology and will allow for continued development of a closed-loop neuroprosthesis for bladder control.
Despite contemporary anthropology's growing interest in 'futures' , there has been an absence of sustained dialogue concerning the vital role of anticipation in everyday life. Seeking to bring much needed attention to the first-person perspective on futurity, in this introduction to the special issue we situate anticipation within the temporality of lived experience. Drawing on premises from anthropological studies of experience (particularly phenomenological approaches), we frame the experiential approach to anticipation by highlighting the parameters of its cross-cultural and intercontextual variability. We argue that anticipatory experience provides a crucial locus for ethnographic inquiry into the disparate and polysemous manifestations of futures in everyday life. We then seek to demonstrate how anticipation thus conceived may be productively integrated with numerous ongoing themes within contemporary anthropological scholarship. Finally, we introduce the individual contributions to the issue.
This chapter theorizes the phenomenological potential of anthropology through an examination of what we will call the “eventive ground” of ethnographic knowledge. Though anthropologists and phenomenologists have reacted to one another’s work, including the now famous early correspondence between Husserl and Levy Bruhl (see Sato, 2014; Throop, 2018), it has only been over the past few decades that some anthropologists began to distinguish a genre of a distinctively ‘phenomenological anthropology’ (Desjarlais & Throop, 2011; Katz & Csordas, 2003; Ram & Houston, 2015). Anthropologists have applied and extended phenomenological theory in several respects. By attending to the cultural and social contexts—the conditions of possibility—within which phenomena variously disclose themselves, anthropologists have significantly contributed to research in intersubjectivity and genetic phenomenology. Likewise, anthropologists have frequently drawn from and contributed to the phenomenology of perception, the senses, self-experience, embodiment, emotion, affect, mood, politics, and ethics.
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