Coherent acoustic phonons are generated at terahertz frequencies when semiconductor quantum-well nanostructures are illuminated by femtosecond laser pulses. These phonons-also known as nanoacoustic waves-typically have wavelengths of tens of nanometres, which could prove useful in applications such as non-invasive ultrasonic imaging and sound amplification by the stimulated emission of radiation. However, optical diffraction effects mean that the nanoacoustic waves are produced with spot sizes on the micrometre scale. Near-field optical techniques can produce waves with smaller spot sizes, but they only work near surfaces. Here, we show that a far-field optical technique--which suffers no such restrictions--can be used to spatially manipulate the phonon generation process so that nanoacoustic waves are emitted with lateral dimensions that are much smaller than the laser wavelength. We demonstrate that nanoacoustic waves with wavelengths and spot sizes of the order of 10 nm and 100 nm, respectively, can be generated and detected.

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Polarization-sensitive optical coherence tomography (PS-OCT) combines the advantages of OCT with image contrast enhancement, which is based on its ability to detect phase retardation and the fast-axis angle. Both PS-OCT images and histopathology have demonstrated similar features that allowed differentiation of atherosclerotic structures (i.e., plaques) from normal tissue. Moreover, the picrosirius polarization method was used to confirm PS-OCT assessment of collagen in the fibrous cap of atherosclerotic plaques, and high-frequency (40 MHz) ultrasound images were used to identify calcium in the vessel wall. Our preliminary ex vivo investigation of human aortic specimens indicated that PS-OCT might help to identify atherosclerotic lesions.

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