IntroductionThe clinical manifestations of paragonimiasis are diverse and non-specific, and can easily lead to misdiagnosis. We aimed to analyze the clinical manifestations, laboratory features, treatment, and clinical outcome of children with paragonimiasis in order to improve recognition of this disease and avoid misdiagnosis.MethodsChildren diagnosed with paragonimiasis from August 2016 to July 2022 were included in the study. Information on population informatics, medical history, and laboratory features was extracted from case data. The clinical features of paragonimiasis were retrospectively analyzed.ResultsA total of 45 children were included in this study. All children had, at least, one risk factor. The clinical features mainly included fever, cough, pleural effusion, peritoneal effusion, and subcutaneous nodules. The main imaging findings were alveolar exudation, peritoneal effusion, pleural thickening, and local nodules. The “tunnel sign” finding on computed tomography (CT)/magnetic resonance imaging (MRI) was helpful in establishing the diagnosis of paragonimiasis. After praziquantel treatment, most of the children improved, and one child with cerebral paragonimiasis experienced sequelae.ConclusionMost children with paragonimiasis have a good prognosis, but few children can experience sequelae. Avoidance of untreated water and raw food is a simple, feasible, and effective preventive measure.
Objective: The study aims to explore the value of bionic electrical stimulation as a new clinical therapeutic instrument in the repair of postpartum rectus abdominis separation. Methods: The related literatures at home and abroad were searched and collected, and the research progress of clinical treatment of postpartum rectus abdominis separation was summaried, for the purpose to provide reference value for clinical research of postpartum rectus abdominis separation. Results: There was no study on biomimetic electrical stimulation combined with warm moxibustion belt in the treatment of postpartum rectus abdominis separation in all related literatures. Conclusion: A further and better exploration on the method of bionic electrical stimulation combined with warm moxibustion waistband in the treatment of postpartum rectus abdominis separation. This study is expected to provide a more scientific method for obstetric treatment.
Objective: To investigate the application value of electrostimulation biofeedback therapy in combination with vaginal dumbbell therapy to postpartum pelvic floor dysfunction. Methods: Retrospective analysis of 200 cases of postpartum pelvic floor dysfunction patients discharged from the hospital from January 2016 to March 2019 as study subjects who were excluded other underlying diseases and were randomly divided into two groups of 100 cases per group, using electrostimulation biofeedback therapy combined vaginal dumbbell therapy as a treatment group. The treatment of electrostimulation biofeedback therapy in combination with kegel was treated as a control group. Then the curative effects of the two groups were compared and statistically analyzed. Results: There was no significant difference in EMG value of postpartum pelvic floor treatment, type I muscle strength, type II muscle strength, muscle type I fatigue, type II fatigue and POP-Q detection results between the two groups before treatment, p > 0.05. There were significant differences in type I muscle strength, type II muscle strength and muscle type I fatigue between the pelvic floor muscles and the muscles at the end of the treatment day, the sixth month and one year after treatment, p < 0.05. There was no statistically significant difference at the end of muscle type II fatigue
This IRB-exempt study utilized unembalmed female human cadavers. Sacrohysteropexy was performed on 6 cadavers, by affixing polypropylene mesh posteriorly on the uterus/ vagina and anchoring it to the anterior longitudinal ligament overlying the S1 sacral vertebrae. A 9/16 to 3/4-inch diameter metal washer was placed above the midline uterine fundus and attached to a 6 inch long, 8/32 diameter bolt that was threaded through a small opening created at the uterine fundus, down the cervical canal, and out the vagina. The vaginal end of the bolt was fastened to a waxed surgical filament oriented parallel to the table and over a fixed pulley at the table's end. Successive weights of 0.5 to 4.0 kg (in 0.5 kg intervals) were added to provide increasing loads on the uterine fundus, and the distances traversed by the fundus were recorded. The same process was repeated after completion of a total hysterectomy (with vaginal cuff closure) and subsequent sacrocolpopexy with posterior mesh placement. Data were analyzed using ANOVA for within group comparisons. The mean distances traversed for each weight for the two procedures were compared using Student's t tests (Sigma Plot version 13.0), with P 0.05 considered statistically significant. RESULTS: The mean age of the cadavers was 75.3 years. Average BMI was 26.6 kg/m2. All specimens were white. Average distances (AE standard deviation) in cm pulled with 0.5, 1.0, 1.5, 2.0, 2.5, 3.0, 3.5, and 4.0 kg of traction against the uterine fundus after sacrohysteropexy were 0.7 (AE 0.3), 1.2 (AE 0.5), 1.7 (AE 0.5), 2.2 (AE 0.5), 2.6 (AE 0.6), 2.6 (AE 0.6), 2.9 (AE 0.8), and 3.0 (AE 0.7), respectively. After hysterectomy with sacrocolpopexy, these distances (cm) were 0.7 (AE 0.3), 1.0 (AE 0.4), 1.7 (AE 0.4), 1.8 (AE 0.4), 2.0 (AE 0.4), 2.5 (AE 0.4), 2.7 (AE 0.9), and 3.0 (AE 0.6), respectively. Figure 1 illustrates the distances traversed by the apex for these two procedures. There were no statistical differences in the distances moved between sacrohysteropexy and total hysterectomy/sacrocolpopexy. CONCLUSION: In this study, using each cadaver as its own control, there was no difference in the ability of the uterine fundus (after sacrohysteropexy) compared to the vaginal cuff (after sacrocolpopexy) to resist downward traction of successive weights up to 4 kg, as measured by the apical distance traveled. This suggests that functional support provided by these two procedures may be similar. Further studies are needed to correlate these findings with patient satisfaction, which may vary despite similar anatomic results.
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