SE cytological evaluation is a reliable and effective method for the diagnosis of ALL/LBL.

HD (Table 1). The in-house system performed slightly better in contouring brainstem, parotids, and eyes, while the commercial system performed slightly better in contouring cochleae. The time in completing segmentation for one patient is about 9 minutes and 16 minutes for in-house and commercial systems, respectively. This evaluation suggest that this commercial system may be used in clinic for autocontouring head and neck normal tissues, though further examination of the auto-segmented contours is needed when commissioning the tool for clinical use. Conclusion: Multi-atlas segmentation as a well-developed technique is gradually adopted for clinical use. This multi-atlas contouring system is the first commercial implementation we evaluated with similar performance to our in-house solution.

IntroductionThe clinical manifestations of paragonimiasis are diverse and non-specific, and can easily lead to misdiagnosis. We aimed to analyze the clinical manifestations, laboratory features, treatment, and clinical outcome of children with paragonimiasis in order to improve recognition of this disease and avoid misdiagnosis.MethodsChildren diagnosed with paragonimiasis from August 2016 to July 2022 were included in the study. Information on population informatics, medical history, and laboratory features was extracted from case data. The clinical features of paragonimiasis were retrospectively analyzed.ResultsA total of 45 children were included in this study. All children had, at least, one risk factor. The clinical features mainly included fever, cough, pleural effusion, peritoneal effusion, and subcutaneous nodules. The main imaging findings were alveolar exudation, peritoneal effusion, pleural thickening, and local nodules. The “tunnel sign” finding on computed tomography (CT)/magnetic resonance imaging (MRI) was helpful in establishing the diagnosis of paragonimiasis. After praziquantel treatment, most of the children improved, and one child with cerebral paragonimiasis experienced sequelae.ConclusionMost children with paragonimiasis have a good prognosis, but few children can experience sequelae. Avoidance of untreated water and raw food is a simple, feasible, and effective preventive measure.