Background: We report a case of 34 weeks + gestation with aortic dissection to explore the diagnosis and treatment of this type of pregnant woman and to reduce maternal mortality. Case presentation: This report describes the clinical manifestations of a case of late pregnancy with acute aortic dissection (Stanford A Type). Echocardiography was used to detect the location of the rupture, the extent of exfoliation, the true and false lumen, the presence or absence of thrombus in the false lumen, the degree of aortic regurgitation, etc. After the diagnosis, the patients received surgical treatment as soon as possible. The detection rate and type diagnosis accuracy of ultrasonography for pregnancy complicated with aortic dissection are reliable. The location of the intimal rupture by ultrasound was consistent with the intraoperative findings, and there were no recent complications in the mother and newborn. Conclusion: The third trimester of pregnancy with aortic dissection is dangerous. As a simple, safe and non-invasive method, echocardiography has high clinical value in the diagnosis of pregnant patients with aortic dissection.

Little work has been done on the prediction of papillary thyroid microcarcinoma in female patients who have given birth to children, which may be different from other people. We performed a retrospective review of female patients who underwent thyroidectomy, aiming at identifying special predictors of papillary thyroid microcarcinoma in female patients who have given birth to children. Univariate analysis was used to identify potential covariates for the prediction of papillary thyroid microcarcinoma. Multivariable logistic regression analysis was used to identify independent predictors and construct a regression model based on a training cohort (246 patients) and then the regression model was validated using an independent cohort (80 patients). We found that having not more than one boy, taller-than-wide shape, poorly defined margin, marked hypoechogenicity, and microcalcification were independent risk factors for the papillary thyroid microcarcinoma in multivariate analyses. The combined predictive formula had a high predictive effect for papillary thyroid microcarcinoma (AUC = 0.938 for training cohort and 0.929 for validation cohort, respectively). The combined predictive formula has clinical value in the prognosis of papillary thyroid microcarcinoma and it may be simple and effective to ask fertility condition of patients to increase the US diagnosis accuracy of papillary thyroid microcarcinoma.

<b><i>Introduction:</i></b> Mucinous breast carcinoma is a rare histologic subtype of primary breast cancers accounting for 1–6%. It is a rare histological variant in young patients and usually presents without lymph node involvement, and its pathological response to neoadjuvant chemotherapy is rarely reported. <b><i>Case Presentation:</i></b> Pure mucinous breast carcinoma in a 25-year-old female was treated with neoadjuvant chemotherapy every 3 weeks for 8 cycles. After the fifth cycle, the mass size showed no change. We performed modified radical mastectomy in the left breast and axillary lymph node clearance. However, the pathological report showed a complete elimination of both the breast tumor and axillary lymph nodes, which were filled with mucus but did not contain malignant cells <b><i>Discussion:</i></b> Chemotherapy was profoundly effective against the tumor cells, but ineffective against large amounts of extracellular mucus. Even though the cancer cells were sensitive to chemotherapy, the volume of mucinous cancer couldnot be reduced. <b><i>Conclusion:</i></b> In summary, the evaluation criteria of tumor response to chemotherapy based on maximum diameter only should be considered insufficient for mucinous carcinoma.

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