The aim of this study was to describe a series of confirmed and suspected cases of feline panleukopenia virus (FPV) and in-contact cats in an adoption-guarantee shelter in an FPV-endemic area by reviewing shelter records over a 10-month period (January-October 2010). Cats were divided into three groups: in-contact group - asymptomatic cats that were housed with a FPV fecal antigen (Ag)-positive cat/kitten as part of a litter group (n = 66); FPV-survivors group (FPV-infected survivors) - tested FPV fecal Ag-positive and showed clinical signs of FPV, but survived (n = 27); FPV-non-survivors group (FPV-infected non-survivors) - showed clinical signs of FPV and either tested FPV fecal Ag-positive or were housed with an Ag-positive family member, but did not survive (n = 52). Ages ranged from 3 weeks to 3 years, but most were <6 months old (in-contact group: 79%; FPV-survivors group: 70%; FPV-non-survivors group: 85%). A seasonal peak occurred over summer, but cases occurred year-round. Anorexia, dehydration, fever and diarrhea predominated in the FPV-survivors group, and death was preceded by clinical signs of circulatory shock in the FPV-non-survivors group. Housing litters of kittens with their mother was not associated with improved outcome, perhaps because in this population clinical FPV infection was relatively common in queens arriving at the shelter with susceptible litters.
Increased blood pressure during the hypertensive period was likely attributable to increased NE spillover rate, which resulted in a significant increase in plasma NE concentration. Analysis of these results suggests that central sympathetic outflow was increased and may be responsible for the pathogenesis of high blood pressure during the acute phase of renal vascular hypertension in dogs.
Context Contamination of feedstuff with mixed mycotoxins is one of the frequent problems found in broiler chicken production, especially in tropical countries with a hot and humid climate, such as Thailand. Aims An in vivo study was conducted to examine the effects of Thunbergia laurifolia Linn. (TL) leaves on the growth performance, nutrient digestibility and antioxidant enzyme activity of broiler chicks fed naturally mycotoxin-contaminated feed. Methods In total, 375 1-day-old male Arbor Acre broilers were allotted into five experimental groups, with five replicates each (15 chicks per replicate). The experimental groups were mycotoxin-free basal corn–soybean diet (T1, control), diet with mixed mycotoxins (aflatoxin, fumonisins, tricothecene and ochratoxin, T2), T2 diet but supplemented with 1% (w/w) yeast glucomannan (GM, T3), T2 diet but supplemented with 2% (w/w) TL (T4) and T2 diet but supplemented with both 2% (w/w) TL and 1% (w/w) GM (T5). Feed intake, bodyweight gain, feed conversion ratio, mortality rate, nutrient digestibility and the activity of antioxidant enzymes were measured at Days 21 and 42. Key results Broilers in T4 and T5 groups had a significantly (P < 0.05) higher nutrient digestibility than those in the other groups at Day 42, while broilers in the T3, T4 and T5 groups had a significantly (P < 0.05) higher glutathione peroxidase activity than those in the other groups. There was no difference in the growth performance among the groups, except chicks that received the mixed mycotoxin-contaminated feed had a higher feed conversion ratio and ate more feed than did those in the control group. Conclusion It is concluded that 2% TL and 1% GM helped ameliorate the adverse effect of mycotoxin, improving nutrient digestibility and increased the glutathione peroxidase activity, but without a significant change in growth rate. Implications Herbal plant TL can be used as an alternative mycotoxin adsorbent in broiler production.
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