Introduction Prurigo pigmentosa (PP) is an underrecognized disease in the Western population. Our aim is to describe the clinical features and follow-up outcomes of Caucasian patients diagnosed with PP. Methods This case series was conducted in the dermatology outpatient clinic of a tertiary hospital. Patients with confirmed PP from May 2020 to June 2021 were included in the study. Patient demographics, clinical features, potential triggers, treatment and follow-up data were recorded. Results A total of eight patients with female predominance were identified. The mean age of the patients was 24.5. The duration of symptoms ranged from four days to six months. All patients presented with pruritic, papular or papulovesicular lesions. Net-like hyperpigmentation was also present at the initial visit in two patients, in whom the duration of the symptoms was the longest. Lesions were most commonly located on the chest and back. Six of eight patients reported alteration of diet that potentially led to ketosis. Doxycycline 200 mg daily for two weeks led to a complete response in all six medically treated patients. Duration of follow-up ranged from 1-14 months (mean: 7.2 months). In five patients with a follow-up duration of more than three months, postinflammatory hyperpigmentation was resolved without any treatment. Only one patient had a recurrence. Conclusion PP does not seem to be a rare disease. Young women are most commonly affected, and ketosis stemming from decreased calorie intake may be the etiological factor in the majority of the patients. Dermatologists should be familiar with early signs of PP in order to minimize unnecessary therapies, recurrences and long-lasting hyperpigmentation.

The present study has three main aims; a) to investigate the relationship between the tumor grade (TG), type (TT) and size (TS) on the renal carcinoma cancer (RCC) types, and demographic features of the patients such as gender and age, b) to find out the correlation between KI67 proliferation index and COX-2 and CD117 on the RCC, and c) to find out whether the immunohistochemical (IHC) reagents can determine the prognosis of some renal tumor diseases.In this research, 50 cases with RCC in Dicle University Hospital (30 clear cell type, 8 multi-lobular type, 5 sarcomatoid type, 4 papillary type, 3 chromophobe type), and 1 with radical nephrectomy were investigated retrospectively.The TG was carried out using Fuhrman grading system (FGS) and IHC examination was carried out on KI67, COX2, and CD117.The results of the present study did not indicate that gender had any effects on tumor parameters, but CD117 and age had an effect on CD117 and COX2. The results indicated strong correlations between tumor parameters such as TT and TG and CD117, KI67, TG and TT and CD117, and COX2 and KI67.

Aims: The present study aims to find the relationship between the COVID-19 pandemic and early pregnancy abortions.   Methods: The abortion materials observed in the endometrial curettage cases between March 11 and November 30 during the 2020 pandemic period were compared with the those were observed at the same time in 2019. The placentas of COVID-19 positive patients and those of early abortion in the previous year were compared. Furthermore, the relationship between the blood type and covid 19 related abortions were examined. This retrospective study applies various statistical tests to analyze the relationship between COVID-19 and abortions. Findings: The data collected from the samples in 2019 and 2020 were analyzed statistically. Significant differences were found between the causes of miscarriages in 2019 and 2020. Conclusion: The results indicated that there were significant vascular changes in the placentas of pregnant women among the cases of early abortions due to COVID-19 during the pandemic period. In addition, a significant relation was found between ARH+ blood type and COVID-19 on miscarriages. The results suggest that COVID-19 is one of the main causes of early pregnancy abortions.