Background This descriptive study was conducted in order to determine the self-respect and school success of the healthy siblings of the trainable mentally disabled children. Methods The data of the study was collected by informative data form and Coopersmith Self-Esteem Scale between. The school grades of the healthy siblings at the end of the year were obtained from e-school system. The healthy siblings of 91 mentally disabled children who are getting private training and who have siblings were icluded in the study. Results The healthy siblings of the mentally disabled children icluded in the study, 42.8% were between the ages of 12-14 and 57.1% were female, 42.8% were attending second-level primary school classes. The self-respect point average of the healthy siblings of the mentally disabled children was 59.2 ± 14.9; and 69.2% of them had medium level, 27.5% of them high level of self-respect. The self-respect of the healthy siblings was affected by the gender of the mentally disabled sibling and the employment status of the father. The school success level of 60.4% of the healthy siblings at the end of the year was found to be 'good'. Conclusion Supporting the self-respect and school success of the healthy siblings of the mentally disabled children in a way that they would not be affected by their siblings' disability, the families' sparing enough time for the daily needs of the healthy children and their performences at school, improving the cooperation between parents. Background and aims Continuous quality improvement (QI) in healthcare is necessary. However many publications prove that often the implementation of innovations fails in daily hospital practice. We found a lack of knowledge and skills within the executing staff of our children's clinic in this field. The aim was to develop and realise an efficient and effective training to empower the responsible staff nurses in order to improve the success rate of QI implementation projects on the wards. PO-0891Methods After a critical analysis we developed basic principles for this training:· 'learning on the job'; students are using their own project during the course · focus on key elements of implementation and necessary competencies · immediately applicable in daily practice · the use of already in-hospital available knowledge · thorough quantitative and qualitative evaluations (oral and written). Results In 2013 we developed, realised and evaluated this implementation training; · developed by 6 professionals from 4 different fields · training in 4 daily periods (afternoons) in a 3-4 weeks interval · based on 4 implementation key-topics and 7 implementation competencies · 14 students; simultaneously invested in their own QI projects · student-scores (scale: 1-5) mean total training: 3.5 · high scores: applicability (4.4), personal learning efficiency (3.6), trainers (3.9). Discussion/conclusion We successfully designed and realised a training to improve the implementation knowledge and skills of the nursing staff. At present we are improving the train...

chance for keeping the acquired attitudes, behaviour and habits in the following years is the highest. As in many subjects, giving the importance to sexual education in this period has many benefits regarding development. This descriptive study was carried out in order to determine knowledge levels and attitudes of doctors and nurses regarding children's sexual development and sex education. Methods The design of the study is descriptive. The study was conducted with doctors and nurses who work at various clinics of two state hospitals located in the Istanbul province. A total of 138 doctors and 150 nurses work at these hospitals. Results It was determined that the majority of cases were female and were aged more than 36 years. 63.5% of the cases have bachelor's degrees and 62.1% were medical doctors. It was determined that the number of correct responses given by the cases regarding some behaviours observed in children aged between 3-6 years and children's sexual development and sex education showed significant differences according to age group, marital status, status of having children, educational status, and occupation (Table 1). Conclusions All of our cases think that it is necessary to provide sex education for children and the majority of cases think that sex education should be provided for children aged between 7-12 years. Introduction Parents whose child is admitted in a hospital are often overwhelmed by an oncoming discharge. Especially when care has to be continued at home, parents instructions are provided only shortly before discharge. As a result discharge may be suboptimal or hospitalisation may be prolonged. The question arises whether family centred care contributes to a more effective and efficient discharge management. Method We studied the literature, organised 4 focus group discussions with 21 nurses in total, and distributed a survey among 15 parent couples. Results Results from several studies show that parents' participation reduces the time of hospitalisation by circa 3 days. In the focus group discussions nurses recognised that the moment of discharge is mainly based on medical criteria. As a result parents instructions start at a late moment, must be performed in a short period of time and sometimes increases the length of stay. The surveys showed that all parents feel responsible for the care of their child during hospitalisation. Of the parents, 64% mentioned that they are involved in the discharge planning, that started at admission. However, only 34% of the parents stated to be informed about discharge criteria. Conclusion Parents' participation shortens the length of stay in hospital. However, the present discharge procedure is not sufficiently family centred and oncoming discharge is not discussed timely. We recommend to discuss discharge planning on a daily base within the team of care providers including the parents, and to involve parents in the discharge manangement. PO-0871

Toll-like receptor 1 (TLR1) recognises lipopeptides with TLR2, and affects immune response to Mycobacterium tuberculosis infection. Here, we report results of the first case-control paediatric study of the TLR1 single-nucleotide polymorphisms and susceptibility to tuberculosis (TB). A paediatric case-control study enrolled 340 TB patients and 366 healthy controls, all Han Chinese from North China. Significant differences of the allelic and genotypic distributions of rs5743618 in TLR1 gene were observed between TB group and control group and, G allele of rs5743618 was associated with increased risk for TB (OR: 2.40, 95% CI: 1.41-4.07, p = 0.0009). In addition, after stimulated with inactivated lysate of Mycobacterium tuberculosis strain H37Rv, whole blood samples from children with the rs5743618 GT genotypes showed a decreased level of Interleukin-12p40 (IL-12p40), Tumour Necrosis Factor-a (TNF-a) and CXC chemokine ligand 10 (CXCL10) production. To conclude, TLR1 rs5743618 G allele was found associated to susceptibility to TB in Han Chinese paediatric population. TLR1 rs5743618-GT genotype carriers may have reduced immune response to MTB infection although further study is warranted to test this conclusion. Introduction Infants in hospital experience pain regularly. It is an important nursing task to observe parameters of pain, because an infant is not able to express itself verbally. The question arises in which way and to what extent parents can play a role in recognising and diminishing pain experienced by their child. Method Involvement of parents in pain management has been investigated by means of a literature search and a survey among nurses. We also explored how parents' involvement could be increased in an effective way. Results Research shows that parents' ínvolvement in pain management is effective. When parents were given an active role, there was a quicker response to pain signals and the child experienced less pain. PS-327 PARENTS: THE BEST PARTNER IN PAIN MANAGEMENTParents' involvement is also feasible. A structured method of providing information increased knowledge of parents. In addition to oral information, demonstrations and videos were of extra value. However, in daily practice parents' involvement in pain management is limited. Parents did not always receive oral (55%) or written (4%) information about pain management.Nurses indicated more parents' involvement than is experienced by parents themselves.The survey showed that 96% of nurses believe that parents are actively involved in pain recognition and 85% thinks that parents play an active role in pain reduction. However, only 53% of the nurses think that parents are actually able to decrease pain. Conclusion Parents' participation in pain recognition and pain reduction is effective. Parents can be trained by means of structured methods of information, demonstrations and videos. Background and aims Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis, is a major cause of morbidity and mortality worldwide. Although the wid...