Greenhouse plant production involves a number of processes such as transpiration, condensation, photosynthesis, and climate control. Such processes, in turn, set off mass and heat transfer phenomena that influence not only the quality and quantity of crop production but also its environmental cost. While these processes have considerably been analyzed in separate, they strongly interact with one another. For instance, increased radiation (mainly thermal infrared) increases temperature, reduces humidity, consequently increases transpiration, and affects CO 2 exchange as well as other reaction rates. Computational fluid dynamics (CFD) is a numerical tool with a solid physical basis which allows, through the construction of a computational model, to simulate the fluid flow environment. Heating, ventilation, and condensation have been analyzed in the greenhouse environment with CFD techniques. The current challenge is the interaction of these processes and their impact on the production system. The present work summarizes some CFD investigations carried out in this topic, in order to analyze the processes of heat and mass transfer in a greenhouse for agronomic purposes.In greenhouse crop production, climate has peculiar considerations, because the most important data is the impact of the environmental factors on the crop cycle. The cultivation of plants requires a sufficient amount of light, a specific range of temperature, humidity, and CO 2 , among other requirements. These requirements are primarily influenced by the greenhouse design and size and vary according to the local climate conditions. For instance, the radiation quantity inside the greenhouse depends on whether greenhouses are built with PVC or glass, because the surface material is the element to optimally use solar radiation for the required lighting [1].Recently, heating, ventilation, and air conditioning (HVAC) systems have been extensively used in urban spaces, such as offices or stores, at agriculture area, and specifically in greenhouses. For instance, HVAC has been used in buildings in order to analyze the optimization and comfort inner Officine's and several uses. In greenhouses, the concept is incipient, even though the application of the ventilation and calefaction systems as a method to climate control in cold and warm regions is nothing new.The climate produced in a greenhouse is the result of complex mechanisms involving the processes of heat and mass exchange. The internal climate is strongly dependent on the outside conditions, especially in unheated greenhouses. In greenhouse climate models, the parameters of the internal climate such as air, soil, and crop temperatures as well as air humidity are calculated using energy and water vapor balances for the various components of the system [2].Climate in the greenhouse is a consequence of radiation crossing the cover material, usually plastic. After that, climate condition is a strong relationship between several factors, temperature, humidity, wind velocity, and the solar radiation. Environ...