Endogenicity has been considered to have a major predictive value as to the therapeutic response to antidepressants. Two recently introduced measures of endogenicity (the Michigan Discriminant Index and the Hamilton Endogenomorphy Subscale) were investigated regarding their potential predictive value. It was concluded that, in a group of selected depressive patients, neither the Michigan Discriminant Index, nor the Hamilton Endogenomorphy Subscale, had a predictive value concerning short-term response to antidepressants.
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