Fenbendazole has a broad spectrum of activity against immature and adult helminths of the intestinal tract and lungs at an oral dose of 5-7.5 mg/kg. This compound has a wide margin of safety in domestic animals without teratogenic side effects. Data are given on metabolism, mode of action and excretion.

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101Summary Death, poor condition and unsatisfactory breeding performance in a rabbit colony was attributed to infection with Passalurus ambiguus.The trouble disappeared after treatment with 50 ppm fenbendazole in the food for 5 days. In laboratory trials 12·5 ppm for 5 days eliminated more than 99% of adult and most immature pinworms, 25 and 50 ppm eliminated all immature and adult pinworms. These doses were also effective against Obeliscoides cuniculi.

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