Recent research shows that a bacterial life form, Erysipelothrix insidiosa, can produce rheumatoid arthritis in deer, swine, and dogs, and that a number of animals, including man, birds, and fish, may be infected by the organism. Examination of the archaeological record suggests that both cultural and biological variables may be interrelated in the maintenance of some forms of arthritis over long periods of time in geographically disparate populations. Re-examination of Cherokee folk beliefs concerning arthritis suggests that they had some recognition of this connection, and it also suggests that they had some recognition of this connection, and it also suggests that the term "magical" may relate more to the world view of the observer than to any actual inability of preliterate peoples to draw causal relations on the basis of their own intimate knowledge of their environments.
Summary
Arthritis in swine, produced by Erysipelothrix rhusiopathiae, resulted in increased serum total protein and globulin levels. Increased plasma fibrinogen and serum viscosity also developed. A positive R‐A slide test occurred in severely affected animals. These changes could be correlated with the clinical signs and with the periods of exacerbation and remission.
Zusammenfassung
Veranderungen der Serum‐ und Plasmaproteine bei arthritischen Schweinen
Eine durch Erysipelothrix rhusiopathiae verursachte Arthritis führte bei Schweinen zu einem Ansteigen des Gesamt‐Serumprotein‐ und des Globulinspiegels. Außerdem stiegen das Plasmafibrinogen und die Viskosität des Serums an. Bei schweren Fällen verlief der R‐A‐Objektträgertest positiv. Diese Veränderungen konnten mit den klinischen Erscheinungen und mit Perioden der Verschlechterung oder vorübergehenden Besserung der Erkrankung in unmittelbare Beziehung gesetzt werden.
Résumé
Modifications des protéines sériques et du plasma chez les pores arthritiques
Une arthrite provoquée par Erysipelothrix rhusiopathiae provoquait chez des porcs une augmentation des protéines sériques totales et une élévation du taux sanguin des globulines. En outre, le fibrinogène plasmatique et la viscosité du sérum se trouvaient augmentés. Dans les cas graves, le test «R‐A» sur porte‐objet, donnait un résultat positif. Les modifications enregistrées pouvaient être mises en parallèle avec les symptômes cliniques et avec les périodes d'exacerbation ou de rémission passagère de la maladie.
Resumen
Alteraciones de las proteinas séricas y plasmáticas en cerdos artríticos
Una artritis producida por Erysipelothrix rhusiopathiae, condujo en cerdos a un aumento del nivel de la seroproteina total y de la globulina del suero. Además aumentaron el fibrinógeno plasmático y la viscosidad del suero. En casos graves, resultó positiva la prueba R‐A sobre porta. Estos cambios pudieron correlacionarse estrechamente con los síntomas clínicos y con los periodos de empeoramiento o mejoría pasajera de la enfermedad.
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