Summary.A histological study of 30 spontaneously diabetic dogs and 5 spontaneously diabetic cats is presented. --The islets of Langerhans and the B cells were strongly reduced in number in a large majority of the diabetic dogs. The B cells were often degranulated and hydropic. In cases of longer duration, the islets were scarce and B cells could no longer be found. --In contrast to the findings in diabetic dogs, all five cats showed numerous islets and B cells. However in 4 cats, the B cells showed complete degranulation and hydropic changes, as in the dogs. In one cat, the B cells had a normal appearance. Extensive hyalin deposits were found in the stroma of the islets in 2 cats. In one cat, an islet showed a dense lymphocytic infiltration. --No lesions identical to human diabetic glomerulosclerosis were found in any of the dogs or cats. The changes most frequently observed were a variable degree of thickening of the mesangial stalk of the glomerular capillaries, and an hypertrophy of the wall of the afferent arteriole. Scars resulting from chronic pyelonephritis, were found in a few dogs and cats. --Accllular, non-functionM capillaries, with degeneration of pericytes ("ghost-cells")were found in larger numbers in the retinas of the diabetic dogs than in non-diabetic control dogs.
In this paper, the treatment of a complicated Achilles tendon defect with a composite lateral arm flap with distal design of the skin paddle has been presented. The extended portion of the flap was sufficient to restore adequate contour to the posterior aspect of the ankle, and reinervation showed good protective sensation at 1 year. In terms of resurfacing, the use of the reinervated lateral arm flap with a distal design of the skin paddle seems advantageous. The weakening of the reconstructed Achilles tendon, although without clinical incidence and impairment of elbow extensors at this stage, may indicate that a better substitute than the triceps tendon has to be found. Nevertheless, we would best reconstruct such an Achilles tendon defect by the same technique because of the well vascularized autologous tissue it provides, limiting the risk of infection.
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