SUMMARYThe detectability of peste des petits ruminants (PPR) viral antigen in both ante-mortem secretions and necropsy samples from experimentally infected goats was investigated by both the agar gel precipitation test (AGPT) and counterimmunoelectrophoresis (CIE). Viral antigen was detected from 42'6 % of the samples tested by the AGPT and 80-3 % by CIE. The detection of viral antigen in a high proportion of the ocular and nasal secretions as well as the faeces and buccal scrapings, particularly from those collected within seven days of the onset of fever, by both techniques, would seem to obviate the need for lymph node biopsies or post-mortem samples in order to make a diagnosis of PPRV infection.
We present details of a family who show a high incidence of both intracranial saccular aneurysm and infundibular widening. Familial aneurysms are compared with aneurysms occurring in the general populations with regard both to site distribution and age of onset of symptoms. The possibility of infundibular widening being preaneurysmal is further discussed. It is highly likely that the mode of inheritance in familial cases is one of dominance.
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