A new class of narrowly dispersed nanosize hexagonal MOF rods from Mn(III)-porphyrin and In(III) was obtained. The length of MOF rods was controlled by simple change of reaction times. Furthermore, the oxidation of styrene has been successfully demonstrated with Mn(III)-porphyrin MOF rods and their reusability has been also tested.

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Guide me: Laser confocal microscope photoluminescence (LCM-PL) and optical waveguiding characteristics for tin(IV) porphyrin-based microcrystalline rods and plates were investigated. The efficiency of optical waveguiding for the rods (0.04 μm(-1)) was five times better than for the plate, due to stronger π-π interaction and a short layer distance (3.035 vs. 3.328 Å).

The aim of this study was to evaluate clinical manifestations, age distribution and risk factors of adverse drug reactions (ADRs) of statins. Korean Adverse Event Reporting System (KAERS) database records (July 2009-June 2014) on statin-treated adults were used. ADRs classified as 'certain', 'probable' and 'possible' based on the WHO-Uppsala Monitoring Centre criteria were analysed. The frequency of ADRs was compared between adults (18-64 years) and older people (age ≥65 years) groups. In total, 2161 ADRs from 1690 patients (579, 34.3% older people) were included for analysis. Mean patient age and ADRs per patient were 60.46 ± 12.72 years and 1.28, respectively. ADRs were reported with atorvastatin (48.4%), rosuvastatin (23.0%), pitavastatin (10.4%) and simvastatin (9.1%). The frequent ADRs were gastrointestinal (421 events, 19.5%), musculoskeletal (331, 15.3%), skin (312, 14.4%) and hepatobiliary disorders (286, 13.2%). Skin disorders were significantly more frequent in adults compared to those in older patients (16.3% versus 12.4%, p = 0.021). Common clinical symptoms were myalgia (263 events, 12.2%), dyspepsia (133, 6.2%) and pruritus (103, 4.8%). Myalgia was more frequently reported in adults (12.7% versus 9.5%, p = 0.039) and dizziness was more frequent in older people (3.4% versus 5.8%, p = 0.015). According to KAERS data, leading statin ADRs were gastrointestinal and musculoskeletal disorders. Myalgia and dyspepsia were the common clinical symptoms.

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