COVID-19 research has relied heavily on convenience-based samples, which—though often necessary—are susceptible to important sampling biases. We begin with a theoretical overview and introduction to the dynamics that underlie sampling bias. We then empirically examine sampling bias in online COVID-19 surveys and evaluate the degree to which common statistical adjustments for demographic covariates successfully attenuate such bias. This registered study analysed responses to identical questions from three convenience and three largely representative samples (total N = 13,731) collected online in Canada within the International COVID-19 Awareness and Responses Evaluation Study ( www.icarestudy.com ). We compared samples on 11 behavioural and psychological outcomes (e.g., adherence to COVID-19 prevention measures, vaccine intentions) across three time points and employed multiverse-style analyses to examine how 512 combinations of demographic covariates (e.g., sex, age, education, income, ethnicity) impacted sampling discrepancies on these outcomes. Significant discrepancies emerged between samples on 73% of outcomes. Participants in the convenience samples held more positive thoughts towards and engaged in more COVID-19 prevention behaviours. Covariates attenuated sampling differences in only 55% of cases and increased differences in 45%. No covariate performed reliably well. Our results suggest that online convenience samples may display more positive dispositions towards COVID-19 prevention behaviours being studied than would samples drawn using more representative means. Adjusting results for demographic covariates frequently increased rather than decreased bias, suggesting that researchers should be cautious when interpreting adjusted findings. Using multiverse-style analyses as extended sensitivity analyses is recommended. Supplementary Information The online version contains supplementary material available at 10.1007/s10654-022-00932-y.

Objective:This scoping review aims to identify and understand the different tools and methods used in studies in the field of human eating behavior to assess, measure, or classify participants’ ambivalence toward food and diet, as well as to identify which tools and methods are most frequently employed.Introduction:People's attitudes toward food and eating behaviors are often ambivalent (simultaneously positive and negative), making it harder to change eating behaviors in favor of a healthier diet. This highlights the importance of resolving diet-related ambivalence. Identifying and understanding the different methods used in the literature to assess attitudinal ambivalence toward food and diet will provide researchers with a range of options to choose from for future studies.Inclusion criteria:We will include peer-reviewed studies as well as preprints that assess the ambivalence of human participants toward food and diet, regardless of sex, age, or other sociodemographic factors. We will exclude studies in which the methods used to assess ambivalence are not detailed or cannot be reproduced, as well as studies that assess the ambivalence of participants toward farming and agricultural methods or toward methods of food production and preparation.Methods:This review will follow the JBI methodology for scoping reviews. Peer-reviewed studies will be retrieved from MEDLINE, PsycINFO, Web of Science, Food Science Source, FSTA, and CINAHL, while preprints will be retrieved from PsyArXiv and MedArXiv. Two independent reviewers will screen the articles. All relevant extracted information will be presented as tables and a descriptive summary of the findings.

Background The pharmacological treatment of cardiovascular diseases and type 2 diabetes mellitus reduces the risk of cardiovascular events.; however, most patients do not adhere to the treatment. There are several self-reported measures for assessing medication adherence. Identifying the instruments with the best psychometric evidence is essential for selecting an accurate measure. The aim of this study is to critically assess, compare and synthesize the quality of the measurement properties of patient-reported outcome measures to access medication adherence among patients with cardiovascular diseases and/or type 2 diabetes mellitus. Methods This protocol is reported according to Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) and the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) guidelines. The following databases will be searched: Web of Science, SCOPUS, PubMed, CINAHL, EMBASE, LILACS, PsycINFO and ProQuest. Discussion This review will provide a detailed assessment of the measurement properties of self-reported medication adherence instruments in patients with cardiovascular diseases and/or type 2 diabetes mellitus to support clinical practice and research. Systematic review registration PROSPERO CRD42019129109.

O presente artigo traz um relato de experiência acerca de atividades de promoção da saúde, no âmbito da extensão comunitária, com enfoque na prática de atividade física e alimentação saudável. Trata-se de um projeto realizado por docentes e estudantes voluntários vinculados a um programa de pós-graduação, em parceria com uma escola pública estadual no município de Limeira, São Paulo ao longo do ano letivo de 2018. O objetivo do projeto foi, por meio de atividades participativas e dinâmicas voltadas para crianças e adolescentes no ambiente escolar, promover mudanças de hábitos de saúde apontados como desafiadores pela comunidade escolar. As crianças e adolescentes que participaram das atividades declararam melhora em seu conhecimento e conscientização acerca da prática de atividades físicas, alimentação saudável e higiene pessoal, ao passo que os voluntários consideraram a iniciativa como oportunidade ímpar de formação por meio do compartilhamento dialógico de saberes e experiências entre as partes envolvidas.

Air pollution is comprised of several substances, including particulate matter (PM). Exposure to air pollution may trigger alterations in DNA methylation thus modifying gene expression patterns. This phenomenon is likely to mediate the relationship between exposure to air pollution and adverse health effects. The purpose of this study was analyzing the effects of exposure to PM 2.5 during pregnancy or lactation and whether it would cause multigenerational epigenetic alterations in the promoter region of the genes Pdx1 and NEUROG3 within mouse pancreatic islets. Our results show that maternal exposure to PM 2.5 led to an elevation in blood glucose levels within the two following generations (F1 and F2). There was also an increase in DNA methylation in the aforementioned promoter regions accompanied by reduced gene expression in generations F1 and F2 upon F0 exposure to PM 2.5 during pregnancy. These data suggest that maternal exposure to PM 2.5 from air pollution, particularly during pregnancy, may lead to a multigenerational and lifelong negative impact on glucose homeostasis mediated by an increase in DNA methylation within the promoter region of the genes Pdx1 and NEUROG3 in pancreatic islets.