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The rheological profiles of commercial corticosteroid nasal spray suspensions (Beconase, Nasacort, Flixonase, and Nasonex) were compared using shear and extensional techniques. Thixotropy/shear thinning was investigated (Carri-Med CSL100, concentric cylinder geometry) by (a) the generation of flow curves at low (100 sec-1) and high (1200 sec-1) maximum shear rates and (b) determination of equilibrium shear viscosities at constant shear rates of 10 sec-1, 100 sec-1, or 1200 sec-1. Extensional properties, on which droplet breakup and size depend, were examined using digital camera photography of droplet evolution and the length any trailing filament formed when the suspension was extruded from a 10-ml syringe at 500 microliters/min. All the nasal suspensions were shear thinning and were also thixotropic to varying degrees. The absence of significant thixotropic recovery at short times (5 min) for all the sprays implies that thixotropy is not necessarily the controlling factor for prolonged residence of the spray in the nasal cavity, but rather that it is the high viscosities present in all four sprays, even after structure breakdown. Preliminary extensional flow data identified differences among the four sprays, with extensional filament lengths increasing in the same rank order as the lowest shear rate (10 sec-1) equilibrium viscosities.

Abstract. Ice fabrics – the distribution of crystal orientations in a polycrystal – are key for understanding and predicting ice flow dynamics. Despite their importance, the characteristics and evolution of fabrics produced outside of the deformation regimes of pure and simple shear flow has largely been neglected, yet they are a common occurrence within ice sheets. Here, we use a recently developed numerical model (SpecCAF) to classify all fabrics produced over a continuous spectrum of incompressible two-dimensional deformation regimes and temperatures. The model has been shown to accurately predict ice fabrics produced in experiments, where the ice has been deformed in either uniaxial compression or simple shear. Here we use the model to reveal fabrics produced in regimes intermediate to pure and simple shear, as well as those that are more rotational than simple shear. We find that intermediate deformation regimes between pure and simple shear result in a smooth transition between a fabric characterised by a girdle and a secondary cluster pattern. Highly rotational deformation regimes are revealed to produce a weak girdle fabric. Furthermore, we provide regime diagrams to help constrain deformation conditions of measured ice fabrics. We also obtain predictions for the strain scales over which fabric evolution takes place at any given temperature. The use of our model in large-scale ice flow models and for interpreting fabrics observed in ice cores and seismic anisotropy provides new tools supporting the community in predicting and interpreting ice flow in a changing climate.

<div>Antarctic ice flow shows deviation from the deformation regimes of pure and simple shear. By analysing the vorticity number from surface velocity data it is found that approximately 80% of the flow is outside these regimes. These deformations are both between pure and simple shear, as well as highly rotational, highlighting the need for fabric predictions away from the commonly studied regimes of pure and simple shear. </div><div>We use the numerical scheme SpecCAF, which has been shown to accurately reproduce experimentally observed fabrics with no free parameters, to study ice fabrics in such general deformations. By exploring the parameter space of temperature and vorticity number, we present a definitive classification of fabrics patterns which arise, and construct a universal regime diagram for ice fabrics under general two-dimensional deformation. We find that intermediate deformations see a smooth transition between a cone-shape fabric and a secondary cluster. We present the first investigation of the fabrics produced in highly rotational deformations, which produce a weak girdle fabric with the axis aligned to the vorticity axis. We also show that across deformation and temperature space fabrics only reach a true steady-state above strains of 200%, and there is significant variation in this across the parameter space.  </div>

<p>Understanding the anisotropic flow of ice is likely a key factor for the reliable prediction of the evolution of certain regions of the Earth’s ice sheets. Anisotropy of the crystal lattice alignment of ice grains is typically neglected in the large majority of ice-sheet models, however the viscosity of ice can vary by a factor of at least 9 in different directions, indicating the potential to provide a dominant control. Even though anisotropy can have a large regional influence, its effects are currently poorly understood. For example, it is an open question as to how different varieties of crystal fabrics are produced by different forms of deformation, and how these dynamics vary with temperature.</p><p>To address these questions, we use a continuum-mesoscopic approach, proposed by Faria (2006a) and Placidi (2010) to model the evolution of the ice crystallographic preferred orientations (CPOs). The model assumes strain induced crystal lattice rotation i.e. crystal plasticity with rigid body rotation where parameters representing the following processes are incorporated: the relative importance of basal slip, the magnitude of grain-boundary migration and the magnitude of rotation recrystallization. We solve the system using a new spectral method, which is computationally highly efficient, and able to fully resolve the multiple dimensions of the problem (time, space and the two dimensions of orientation angle). By considering the predictions of the model in the cases of deformation representing shear and compression, the model is determined to reproduce all the detail features observed in ice CPOs evolution such as secondary clusters or cone shapes. The results show excellent agreement with experiments of ice deformation in both shear and compression. The experimental comparison is used to determine the first constraints on three temperature-dependent dimensionless numbers defining the relative important of the recrystallization and slip processes. With these dependencies constrained using shear experiments, the application of the model results is able to reproduce the observations of crystal structure in compressive experiments with no further fitting parameters. The model is thus found to provide good agreement with laboratory experiments  across a range of temperatures, strain rates and flow fields.  Moreover, the predicted patterns correspond qualitatively to those observed in natural ice from cores, with our results providing the first theoretical demonstration of the characteristics of the fabric structure. </p>