Objective
The objective of this study was to identify determinants of stillbirth in Felege Hiwot comprehensive specialized referral hospital, North-west, Ethiopia: 2019. To conduct this study an institutional-based unmatched case–control study was used among 84 cases and 336 controls. Pretested, structured questioner with face to face interview was conducted and some data were also extracted from medical records using a checklist. The data were analyzed by using binary logistics regression. A p-value of < 0.05 was considered as significant at 95% confidence level and the strength of association was measured using odds ratio.
Results
Illiteracy (AOR 3.8, 95% CI 1.4–10.2), sexually transmitted infection (AOR 5.7, 95% CI 1.1–29.7), Premature rupture of membrane (AOR 4.0, 95% CI 1.4–11.3), congenital anomaly (AOR 10.4, 95% CI 2.0–11.2) and history of perinatal death (AOR 10.4, 95% CI 3.7–29.2) were the determinants of stillbirth that increase risk of fetal death. Whereas taking at least two doses of tetanus toxoid vaccine (AOR 0.5, 95% CI 0.2–0.9) and partograph use (AOR 0.2, 95% CI 0.1–0.4) were found to be protective factors for stillbirth. To overcome this problem; empowering female education, facilitating women in taking tetanus toxoid vaccine, sexually transmitted infection prevention, and encourage health professionals to use partograph during labour follow up highly strongly recommended.
Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is coronavirus isolated from SARS patients. As far as the researchers' knowledge, there was paucity of studies conducted in Ethiopia, particularly in the study area. As immune protection is arisen from our blood cells, assessing their level will provide a clue for controlling the disease and monitoring the prognosis. This study will also provide additional information for clinical intervention and patient management. Purpose: This study aimed to investigate the hematological profile and clinical outcome of coronavirus disease-19 (COVID-19) among patients admitted to the Debre Markos Isolation and Treatment Center (DMITC). Material and Methods: A prospective cohort study was conducted among 136 COVID-19 adult patients at DMITC from January 1, 2020 to March 30, 2021. Data related to clinical, hematological profiles and socio-demographic factors were collected, entered into Epi data, and analyzed using STATA 14.2 software. Multivariable logistic regression was applied to determine the predictor variable and a p-value <0.05 was considered significant. Results: Of 136 COVID-19 patients, 28.68% had died. The mean age of patients was 47.21±1.29 years. The hematological profile of the patients revealed that 28% had abnormal leukocyte, 23% abnormal lymphocyte, 44.85% abnormal granulocyte, 22.06% abnormal monocyte, 30.15% abnormal RBC and 87% abnormal platelet counts. The prevalence of anemia was 13.24%. Conclusion: Leukocytosis (mainly granulocytosis and monocytosis) and lymphopenia, were the predominant abnormal findings of complete blood cell count (CBC) analysis of the patient's blood. Most of the patients had abnormally low platelet counts. RBC count and hematocrit determination were the only significant predictors of death. The clinician could manage cases according to the hematological findings of the patients. Further experimental studies should be conducted to determine hematological parameter changes and the clinical outcome of the disease.
Background: Perinatal mortality is defined as fetal death after 28 weeks of gestation and newborn death within seven days. Globally, more than 2.6 million stillbirths and over 2.7 million early neonatal deaths are estimated to occur each year. Each day an estimated 7,300 newborns die from complication during pregnancy, child birth and further neonatal causes and 7000 stillbirth, half of this occurs after labor had started. Almost all (98%) takes place in developing countries and the magnitude of perinatal mortality in the study area was 44 per 1000 pregnancy.
Objective: The objective of this study was to identify determinants of perinatal mortality in Bahirdar town governmental health institutions.
Methods: Institutional based unmatched case control study was conducted .Cases were stillbirths and early neonatal deaths and controls were live births that were survived the first seven days after delivery. A total of 459 participants were involved in this study (153 cases and 306 controls) .Pretested, structured questioner with face to face interview was conducted and some data were also extracted using checklist from their medical records. Multivariable logistic regression analysis was done to analyze the data. A p-value of <0.05 was considered as significant at 95% confidence interval and the strength of association was measured using odds ratio.
Results: Antepartum hemorrhage (AOR 2.55,95%CI;1.23-5.26), obstructed labour (AOR 3.11,95% CI; 2.00-8.38), prematurity (AOR 3.29,95% CI;1.86-5.81), first delay (AOR 2.61,95% CI;1.56-4.39) and second delay (AOR 2.75,95% CI;1.49-5.11) were the determinants of perinatal mortality that increase risk of perinatal death. Whereas partograph use (AOR 0.24, 95% CI; 0.14-0.42) and tertiary education (AOR 0.35, 95% CI; 0.17-0.71) were found to be protective factors for perinatal mortality. Conclusion and Recommendation:The determinants of perinatal mortality were antepartum hemorrhage,prematurity, obstructed labour, first delay and second delay that were increase the risk of perinatal mortality whereas maternal tertiary education and partograph use during labour follow up were the protective factors. But the risk factors were easily identifiable and manageable with the existing health care services while health partograph use in labour follow up and educating females to tertiary education level is better, first and second delay need to avoided during
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