Granulomatosis with polyangiitis (GPA) is a small-vessel vasculitis consisting of necrotizing granulomatous lesions in airways and focal necrotizing glomerulonephritis. However, it may affect other sites such as the skin, central nervous system, eyes, heart, gastrointestinal tract, and liver. We describe a rare case of GPA in which the initial manifestation was the involvement of the parotid gland mimicking a pyogenic abscess.

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21st World Congress on Ultrasound in Obstetrics and GynecologyPoster abstracts system, fetal gender and associate anomalies. All patients were evaluated by two or three examiners with experience in prenatal diagnosis accompanied by geneticist in the examination room. A high resolution instrument model DC-7 (Mindray) was used. Results: A diagnosis of urogenitary system malformations was made in 49 of the 564 fetuses evaluated, corresponding to 8.6% of the total Conclusions: The incidence of urogenitary tract malformation in the present series was about 1.5 times higher than the reported in the literature. Most malformations can be surgically corrected after birth, with a good prognosis in the absence of complex syndromes or associated chromosomal disease. P08.05Screening for fetal heart disease in the second and third trimester by prenatal ultrasonography in a Chinese hospital S. Chen, X. Gong, X. Liang, Q. Li Department of Ultrasonography, Second People s Hospital of Shenzhen, Shenzhen, ChinaObjectives: To investigate multi-views conjoined screening (MVCS) for fetal heart disease in the second and third trimester pregnancy by prenatal ultrasound. Methods: The four-chamber view (FCV) alone, FCV with three vessels and trachea view FCV+3VT, MVCS of 16,500 consecutive fetuses aged from 18 to 36 week were examined to screen for fetal cardiac malformations with color Doppler. Suspected fetal cardiac disease was confirmed by postmortem or postnatal echocardiography and/or surgery. Then, the sensitivities of screening tests were compared among the three methods. Results: 96 fetuses was identified fetal heart disease. The Youden indexes of MVCS (0.9045) were more than FCV (0.5117) and FCV+3VT (0.7972) (P < 0.05), Compared with FCV and FCV+3VT, MVCS was with the most sensitive and lowest missed diagnosis. Conclusions: MVCS is a good method to diagnose fetal heart disease in the second and third trimester pregnancy with the most sensitive and lowest missed diagnosis. Objectives: The 22q11.2 deletion is a common chromosomal deletion syndrome, with a postnatal prevalence of 1 : 4000 newborns, with dominant autosomical inherited and with a wide phenotypical and clinical variability, which includes VeloCardio-Facial syndrome (VCFS/del 22q11), DiGeorge syndrome, Shprintzen, Takao (conotruncal anomaly face syndrome) and Cayler syndrome. The diagnose of this disease is important because it is a multisystemic disease that has different clinical expressions: congenital heart disease (conotruncal defect the most frequent), immunological abnormalities (cellular immunity) endocrynological abnormalities, palate/facial defects, dysmorphies, skeletal and neurological abnormalities. The prenatal prevalence it is probably more elevated than the postnatal prevalence, with a described prevalence of 1.6-11.5% in some series. The aim of our study is to present our experience in prenatal diagnose, using the in situ hybridization (FISH technique) of fetuses with congenital heart disease (CHD). Methods: We studied 110 fetuses with a CHD using FIS...

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