Mycobacterium celatum is a recently described, slowly growing mycobacterium of still undefined clinical relevance. A retrospective study of seven patients was conducted to further elucidate the clinical presentation and prognosis of infection due to M. celatum in patients with AIDS. Three patients had an exclusively pulmonary infection and 3 had disseminated infection (including 2 patients with pulmonary and extrapulmonary involvement), and 1 patient had an exclusively extrapulmonary disease. Fever, weight loss, and productive cough lasting for >2 weeks were the most common symptoms. Chest radiographs showed diffuse or focal interstitial infiltrates without cavitation. The recovery of M. celatum from one patient was definitively determined to be clinically irrelevant. Our findings indicate that M. celatum may cause serious disease in patients with advanced human immunodeficiency virus-related immunosuppression. M. celatum infection appears to be responsive to antimycobacterial chemotherapy; however, further studies are needed to establish the optimal drug combination for this indication.

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New technologies and emissions controls have been developed for the production of charcoal, but are not widely used in the industry. The present study seeks to evaluate the potential environmental impact of these new technologies as compared to traditional ones. A Life Cycle Assessment (LCA) of Brazilian charcoal produced with different technologies without and with the combustion of the gases in burners or furnaces was carried out. The inclusion of furnaces for the combustion of gases reduces all categories of potential environmental impacts by approximately 90% in both a circular masonry kiln and a rectangular masonry kiln with gas combustion. In the process of producing charcoal (gate-to-gate system boundary), in terms of climate change, the rectangular masonry kiln with gas combustion was approximately 63% less impactful than the circular masonry kiln with gas combustion. In the gate-to-gate analysis, the rectangular masonry kiln with gas combustion presented the best performance when not considering NO 2 and SO 2 . Considering these emissions, there were changes in the impact categories of particulate matter emission and terrestrial acidification, and the circular masonry kiln with gas combustion presented better performance (for cradle-to-gate system boundary). The process in a rectangular masonry kiln without gas combustion presented a greater contribution to the categories of terrestrial impact ecotoxicity (98%), due to the emission of acetic acid especially.