General visions in the architectural field shared many concepts. There are numerous indicators for dealing with these concepts, in addition to communicating with deeper areas that formed a source for scientific addition to them. Epistemology is one of these concepts that represent a necessary and essential field and has a fundamental value of knowledge. Epistemology can represent an intellectual expansion to any other field. Therefore, the scope for this study was to investigate influence of that field through its basic concept (epistemology), with common implicit idea of architecture, in addition to clarifying the state of relationship between the two main terms of the research. This research aims to define and study the general frameworks of basic research concepts of epistemology and creativity and their interconnections within architectural propositions to identify their fundamental indicators within a specific theoretical framework that is formed for this purpose after proposing the research problem. The research problem was represented by the weak clarity of cognitive perception correlation between the concepts of epistemology and creativity, and impact of this correlation in architecture, up to applying the terms and indicators of the theoretical framework to an elected and specific architectural product, and then to present, analyze, and discuss the results of that application, reaching to final conclusions. The outcomes have revealed the significant influence of the indicators of general conceptual frameworks for the epistemology relationship with creativity versus the more substantial impact of interactive and detailed structures for that relationship.