<p class="abstract"><strong>Background: </strong>Acne vulgaris is a common, chronic disorder resulting from the inflammation of pilosebaceous unit, present with clinically various forms. It is usually prevalent in adolescent may persist in adulthood. This study was conducted to evaluate the quality of life (QoL) in patients suffering from acne vulgaris.</p><p class="abstract"><strong>Methods:</strong> Hospital based cross sectional study was conducted in 60 patients. Dermatology life quality index (DLQI) questionnaire was used to observe the effect of acne among patients.</p><p class="abstract"><strong>Results: </strong>Total numbers of patients enrolled were 60 (43 females,17 males). The mean age was 24.85±5.63 years. Maximum patients were of the age group 26-30 years (22 patients; 36%) and least were of 31-36 age group. Out of 60 patients, 29 patients had grade II acne followed by 20 with grade I acne, grade III acne was present in 11 patients. Most of the patients 31 (52%) were having “moderate impact” on quality of life followed by 23 (38%) with “small impact” on QOL. There was a significant positive correlation between grade of acne and DLQI (Pearson correlation=0.753, p=0.00).</p><p class="abstract"><strong>Conclusions: </strong>Our study showed significant impairment of QoL in acne patients. DLQI increases with increase in severity of acne. Treatment of acne should not be guided only by the clinical grade of acne, but take into consideration the psychosocial impact the condition has on the patient. Adequate counselling along with early treatment of acne vulgaris is essential in order to reduce the disease related psychosocial sequelae and increase treatment efficacy.</p>

Background: Viral warts are benign proliferation of the skin and mucosa caused by various strains of double stranded DNA human papilloma virus (HPV). MMR immunotherapy of warts is a novel, simple, cost-effective procedure which treats wart by stimulation of non-specific cell mediated immune response to clear HPV virus from the skin. A study to evaluate the role of intralesional measles mumps rubella (MMR) immunotherapy in cutaneous viral warts. Methods: Total 22 patients of both sexes were included in the study. Intralesional MMR 1 unit (0.1 ml) was injected into the largest wart at 2 weeks interval for a maximum of six treatments. Maximum dose of immunotherapy was 0.5 ml for one session and follow up was kept for 3 months duration. Results: Out of 22, 20 patients completed the treatment, 12 patients (60%) shows complete response, 5 patients (25%) shows partial response and 3 patients (15%) shows no response. Conclusions: Intralesional measles mumps rubella (MMR) immunotherapy is an easy, simple, minimally invasive and relatively painless technique, which helps in induction of an adequate immune response leading to resolution of warts.

<p class="abstract">Acne vulgaris is a common skin disorder affecting 80% of people between 11-30 years of age with many experiencing some degree of scarring. Pulsed wave carbon dioxide (CO2) laser resurfacing is a recent addition in armamentarium of treatment options for acne scars. This study focuses on one of the most common type of acne complication - atrophic scars treated with pulsed wave carbon dioxide laser. To evaluate efficacy of pulsed carbon dioxide laser for treatment of mild to moderate atrophic facial acne scars. 10 subjects (6 male and 4 females, aged 22-35 years) with skin type III-V and atrophic acne scars were treated with 4 sessions of carbon dioxide non-ablative laser resurfacing on 6 weeks interval. 7 out of 10 subjects in our study perceived an excellent to good improvement with 2 patients showing fair improvement and 1 patient with no improvement. Adverse effects were limited to prolonged erythema (two patients), and post-inflammatory hyperpigmentation (three patient). Excellent to good clinical improvement observed in 70% of patients with acne scars. This underscore pulsed carbon dioxide laser’s effectiveness in the treatment of mild to moderate atrophic acne scars.</p>

Infection with <em>Mycobacterium tuberculosis </em>or other very closely related strains, as well as the inflammatory reaction of the host, define the disease tuberculosis. Cutaneous tuberculosis constitutes a small proportion of extrapulmonary tuberculosis. Extensive, multifocal involvement of cutaneous tuberculosis is a rare manifestation. We report one such case of tuberculosis verrucosa cutis in a 24 year old immunocompetent male patient.