The swellings in the neck can be caused by innumerable pathological lesions arising from the various anatomical structures lying therein. Multi-Detector CT (MDCT) has now become the new standard in a radiological imaging modality. The utilization of MDCT has resulted in improved resolution and considerable reductions in scan acquisition and display time. Aim and Objective: This study is an effort to assess the role of MDCT in detection, characterization and diagnosing neck pathologies that correlate cytologically. Material and Methods: A study of 50 cases in a clinically suspected neck mass was studied for 1 year. Contrast-enhanced Ct neck was done and Specific CT criteria were used to characterize the mass so that a probable diagnosis could be made. MDCT diagnoses then compared with cytological results to conclude the efficiency of MDCT analysis of neck mass. Conclusion: Multi-detector computed tomography helps in precise anatomical localization and characterization of neck masses. Hence, it will be a method of choice for initial evaluation, preoperative planning, and biopsy targeting and postoperative follow-up. Key Words: Neck mass; Cervical lymph node; Computed tomography; Carcinoma.

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