In subjects with hereditary angioedema, nanofiltered C1 inhibitor concentrate shortened the duration of acute attacks. When used for prophylaxis, nanofiltered C1 inhibitor concentrate reduced the frequency of acute attacks. (Funded by Lev Pharmaceuticals; ClinicalTrials.gov numbers, NCT00289211, NCT01005888, NCT00438815, and NCT00462709.)

Semiconducting nanowires and nanotubes are an emerging class of 1D nanostructures that represent attractive building blocks for nanoscale electronic and photonic devices. For example, inorganic semiconductor nanowires [1][2][3] and carbon nanotubes, [4] show great promise for nanoelectronic devices and integrated nanosystems because they can function both as device components for logic, memory, and sensing applications and also as interconnects. Inorganic semiconductor nanowires are also attracting increasing research interest as building blocks for integrated nanophotonic systems, since they can function as subwavelength optical waveguides, emissive devices, and photodetectors. [1][2][3][5][6][7][8][9][10][11][12] With respect to the latter, photoconductance measurements have recently been reported for a range of single inorganic nanowire devices: InP, [5] ZnO, [6] GaN, [7] and Si, [8] as well as for carbon-nanotube devices.[13]While inorganic nanowires and carbon nanotubes have been explored in depth, the challenge of controlled fabrication of 1D nanostructures based on organic molecular materials suitable for integrated (opto)electronic applications has yet to be as comprehensively addressed. In particular, semiconducting polymers are attractive materials due to their chemically tunable optical and electronic properties, as well as their facility for solution processing. [14,15] 1D nanostructures fabricated from such polymers have been the subject of recent research with regard to their physical, chemical, electronic, and photonic properties. [16][17][18][19][20] However, demonstration of viable polymer nanowire technologies will require the development of reliable methods for the production of such structures with good control over critical parameters such as diameter, length, morphology, and chemical composition. Recently, a new method for the formation of organic nanotubes and nanowires through the wetting of porous anodized alumina membranes has been reported. [20] This method of template wetting using solution-based or molten material does not require specialized apparatus and is broadly applicable across a wide range of organic materials, including small molecules, oligomers, polymers, blends, and multicomponent solutions.[20]In this work, we demonstrate that solution-assisted template wetting may be successfully exploited for high-yield controlled synthesis of poly[(9,9-dioctylfluorenyl-2,7-diyl)-co-(bithiophene)] (F8T2) nanowires. Following liberation from the template and dispersion, our method produces discrete nanowires with average lengths of 15 lm and mean diameters of 200 nm. We report on the electrical characteristics of singlenanowire devices and, further, on the use of single F8T2 nanowires in photoconductivity-based photodetectors. To date, there have been relatively few reports on photoconductivity in 1D polymer nanostructures; for example, Kim and coworkers have reported photoconductance in single bilayer nanotubes comprising poly-(p-phenylenevinylene) (PPV) nanotube cores and carbonized PP...

Zinc-based glass polyalkenoate cements have been synthesised and their potential use in orthopaedic applications investigated. Zinc ions were released from the materials in a rapid burst over the first 24 h after synthesis, with the release rate falling below detectable levels after 7 days. Cement-implanted bone samples were prepared and the released zinc was shown, using energy dispersive X-ray analysis, to penetrate from the cement into the adjacent bone by up to 40 µm. Finally, the cements exhibited antibacterial activity against Streptococcus mutans and Actinomyces viscosus that reflected the pattern of zinc release, with the inhibition of growth greatest shortly after cement synthesis and little or no inhibition measureable after 30 days.

Access to the full text of the published version may require a subscription. The relationship between the nanoscale structure of vanadium pentoxide nanotubes and their ability to accommodate Li + during intercalation/deintercalation is explored. The nanotubes are synthesized using two different precursors through a surfactant-assisted templating method, resulting in standalone VO x (vanadium oxide) nanotubes and also nanourchin. Under highly reducing conditions, where the interlaminar uptake of primary alkylamines is maximized, standalone nanotubes exhibit near-perfect scrolled layers and longrange structural order even at the molecular level. Under less reducing conditions, the degree of amine uptake is reduced due to a lower density of V 4+ sites and less V 2 O 5 is functionalized with adsorbed alkylammonium cations. This is typical of the nano-urchin structure. Highresolution TEM studies revealed the unique observation of nanometer-scale nanocrystals of pristine unreacted V 2 O 5 throughout the length of the nanotubes in the nano-urchin. RightsElectrochemical intercalation studies revealed that the very well ordered xerogel-based nanotubes exhibit similar specific capacities (235 mAh g -1 ) to Na + -exchange nanorolls of VO x (200 mAh g -1 ). By comparison, the theoretical maximum value is reported to be 240 mAh g -1 .The VOTPP-based nanotubes of the nano-urchin 3-D assemblies, however, exhibit useful Submitted to 3 charge capacities exceeding 437 mAh g -1 , which is a considerable advance for VO x based nanomaterials and one of the highest known capacities for Li + intercalated laminar vanadates.

In summary, before, during, or after exercise in a moderately warm environmental condition, neither the addition of a modest amount of clothing nor the fabric characteristics of this clothing alters physiological, thermoregulatory, or comfort sensation responses.