The antibacterial effects of zinc ion migration from zinc-based glass polyalkenoate cements

Boyd, Daniel; Li, H.; Tanner, David A.; Towler, Mark R.; Wall, J. Gerard

doi:10.1007/s10856-006-8930-6

Cited by 120 publications

(89 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Critically, this composition, in particular the inclusion of Zn in the structure, explicates the lack of crystallinity associated with the formation of the apatite layers observed on Zn-GPCs after immersion in SBF [1,9]. Zn-GPCs release clinically beneficial amounts of Zn 2+ from the mantle of set cements for prolonged periods of time to inhibit bacterial colonization of the implant [7]. However, literature shows that Zn is effective at inhibiting the crystallisation of HA [18]; one report states that Zn is 1000 times more effective at inhibiting the crystallization kinetics of hydroxyapatite than magnesium (Mg) [19].…”

Section: Wherementioning

confidence: 80%

See 1 more Smart Citation

TEM analysis of apatite surface layers observed on zinc based glass polyalkenoate cements

et al. 2007

Self Cite

View full text Add to dashboard Cite

Section: Wherementioning

confidence: 80%

“…Secondly, Zn-GPCs set without a significant evolution of heat, when compared with commercial bone cements such as Spineplex ® (Stryker, Limerick, Ireland). Finally, these materials can be tailored to release clinically beneficial ions into surrounding tissues [7]. In addition to Zn, these cements have been synthesized to contain strontium (Sr) [8,9].…”

mentioning

confidence: 99%

TEM analysis of apatite surface layers observed on zinc based glass polyalkenoate cements

et al. 2007

Self Cite

View full text Add to dashboard Cite

“…It has been well established that Zn ions (Zn 2+ ) show antibacterial property [64][65][66]. Recently, Zhu et al [59] introduced plasma immersion ion implantation (PIII) process as a promising method for Zn-incorporation on Ti alloy, which is beneficial to both osteogenic and antibacterial abilities to enhance osseointegration while decreases implant-associated infections.…”

Section: Advantages Of Zn and Its Alloysmentioning

confidence: 99%

Biodegradable Metallic Wires in Dental and Orthopedic Applications: A Review

Asgari

Hang

Chang

et al. 2018

Metals

View full text Add to dashboard Cite

Abstract:Owing to significant advantages of bioactivity and biodegradability, biodegradable metallic materials such as magnesium, iron, and zinc and their alloys have been widely studied over recent years. Metallic wires with superior tensile strength and proper ductility can be fabricated by a traditional metalworking process (drawing). Drawn biodegradable metallic wires are popular biodegradable materials, which are promising in different clinical applications such as orthopedic fixation, surgical staples, cardiovascular stents, and aneurysm occlusion. This paper presents recent advances associated with the application of biodegradable metallic wires used in dental and orthopedic fields. Furthermore, the effects of some parameters such as the surface modification, alloying elements, and fabrication process affecting the degradation rate as well as biocompatibility, bioactivity, and mechanical stability are reviewed in the most recent works pertaining to these materials. Finally, possible pathways for future studies regarding the production of more efficient biodegradable metallic wires in the regeneration of bone defects are also proposed.

show abstract

“…Zinc (Zn) is the second most prevalent trace element in the human body and is reported to stimulate fracture healing of bone (3) , reduces postmenopausal bone loss (4) , improves bone mineralization (5) , and improves skeletal strength (6) . Furthermore, Zn is an effective agent in killing bacterial strains commonly associated with infection in orthopedic surgeries (7) .…”

Section: +mentioning

confidence: 99%

Preparation and Characterization of Zinc-substituted Bioactive Glasses with Sol–gel Method

2015

Egypt. J. Biophys. Biomed. Engng.

View full text Add to dashboard Cite

N PRESENT study, Different bioactive glass samples are prepared based on the following general formula: [65%SiO 2 -(25-X) %CaO-10% P 2 O 5 -X%ZnO)]; Ca 2+ is gradually substituted with Zn 2+(percentages of X= 0, 2, 4, 6, 8 and 10 mol %) by a quick alkalimediated sol-gel method. Development of a calcium phosphate (CP) layer on their surfaces is studied by soaking them in a simulated body fluid (SBF) for different periods. The consequent formation of the CP layer is studied by means of appropriate techniques such as X-ray diffractometry (XRD), Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) with an energy dispersive system (EDXS). The concentration of Ca 2+, P 5+ ions released from the samples into the SBF is measured by using UV-Vis Spectrophotometer and biochemical Kits. The results show that the formation of calcium phosphate layer on glass surfaces is inhibited by ZnO substitution, and strongly dependent on Zn 2+ concentration.Since the discovery of the first bioglass by Hench et al.. several other glass compositions have been imposed to improve the rehabilitation process in surgical applications. One of the important trends in recent studies is incorporation of some ions in the bioglass composition to improve its biofunctionallity. Regarding the stimulatory effects of some cations such as Mg 2+ , Sr 2+ and Zn 2+ on bone formation either by oral administration or local delivering process (2) , the effect of incorporation of these ions on the physical and physicochemical properties of sol-gel derived glasses has been reported. Zinc (Zn) is the second most prevalent trace element in the human body and is reported to stimulate fracture healing of bone (3) , reduces postmenopausal bone loss (4) , improves bone mineralization (5) , and improves skeletal strength (6) . Furthermore, Zn is an effective agent in killing bacterial strains commonly associated with infection in orthopedic surgeries (7) .Despite the numerous works reporting the stimulating effects of zinc, there are also studies that show other effects of zinc ions on bone cells. Popp et al. studied the effect of Zn 2+ -supplemented osteogenic medium on osteoblastic I

show abstract

The antibacterial effects of zinc ion migration from zinc-based glass polyalkenoate cements

Cited by 120 publications

References 33 publications

TEM analysis of apatite surface layers observed on zinc based glass polyalkenoate cements

TEM analysis of apatite surface layers observed on zinc based glass polyalkenoate cements

Biodegradable Metallic Wires in Dental and Orthopedic Applications: A Review

Preparation and Characterization of Zinc-substituted Bioactive Glasses with Sol–gel Method

Contact Info

Product

Resources

About