The article was originally published with two of its authors listed incorrectly; Michelle Write should be Michelle Wright and Lilla Zollei should be Lilla Z€ ollei. We apologize for any confusion this might have caused.
Topographical maps of visual evoked potentials (VEPs) were recorded from 10 possible Alzheimer's disease (AD) patients and 10 control subjects. The purpose of the study was to determine if the two types of VEPs could function as a diagnostic screening for AD. Results of the statistical analysis did not reveal any latency differences between VEPs for the components elicited by either the pattern shift visual evoked potential (PSVEP)--or flash visual evoked potential (FVEP)--elicited components for AD patients compared with the control subjects; however, the information provided insight into results that are frequently lost with conventional evoked potential data. Statistically significant differences in amplitude were found between the P1 and the N2 of the PSVEP at 124, 126, and 130 ms, and at 116 ms for the FVEP.
Previous reports indicate that adaptation measured by the technique of successive magnitude estimations is not found above 30 dB SL (Fishken et al., 1977; and others). Although the present study confirmed this finding at 60 dB SPL for the original procedure, it was found that a modification of the magnitude estimation procedure resulted in significant loudness adaptation at this intensity. Introduction of a 20-dB increment for 5 s, every 30 s, resulted in a marked and statistically significant decline in successive loudness judgements of the 60-dB tone. In addition, the decline in reported loudness magnitude was cumulative and progressive throughout the 7-min duration of the monaural stimulus. This is typical of classical results found with simultaneous dichotic loudness balances.
In the present study, the authors tested the hypothesis that contrast effects confound the Ipsilateral Comparison Paradigm (ICP). Bidirectional referents were used in which base tones of 50 or 70 dB alternated with referents of greater or lesser intensity in a 3.5-min listening period. The contrast hypothesis leads to the expectation that the bidirectional referents would produce opposing effects that should nullify time-based loudness changes in the common base tone. Contrary to that expectation, base-tone loudness declined significantly over time in the context of the bidirectional referents, and the loudness of the referents also declined significantly over time. Thus, the results of the study testified to the validity of the ICP as a contrast-free measure of broad-based loudness adaptation.
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