In this study, we have characterized the efficiency of an Elekta linac in the delivery of gated radiotherapy. We have explored techniques to reduce the beam‐on delay and to improve the delivery efficiency, and have investigated the impact of frequent beam interruptions on the dosimetric accuracy of gated deliveries. A newly available gating interface was installed on an Elekta Synergy. Gating signals were generated using a surface mapping system in conjunction with a respiratory motion phantom. A series of gated deliveries were performed using volumetric modulated arc therapy (VMAT) treatment plans previously generated for lung cancer patients treated with stereotactic body radiotherapy. Baseline values were determined for the delivery times. The machine was then tuned in an effort to minimize beam‐on delays and improve delivery efficiency. After that process was completed, the dosimetric accuracy of the gated deliveries was evaluated by comparing the measured and the planned coronal dose distributions using gamma index analyses. Comparison of the gated and the non‐gated deliveries were also performed. The results demonstrated that, with the optimal machine settings, the average beam‐on delay was reduced to less than 0.22 s. High dosimetric accuracy was demonstrated with gamma index passing rates no lower than 99.0% for all tests (3%/3 mm criteria). Consequently, Elekta linacs can provide a practical solution for gated VMAT treatments with high dosimetric accuracy and only a moderate increase in the overall delivery time.PACS numbers: 87.56.bd, 87.55.de, 87.55.ne

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The electron dynamics of laser wakefield acceleration (LWFA) is examined in the high-density regime using particle-in-cell simulations. These simulations model the electron source as a target of carbon nanotubes. Carbon nanotubes readily allow access to near-critical densities and may have other advantageous properties for potential medical applications of electron acceleration. In the near-critical density regime, electrons are accelerated by the ponderomotive force followed by the electron sheath formation, resulting in a flow of bulk electrons. This behavior represents a qualitatively distinct regime from that of low-density LWFA. A quantitative entropy index for differentiating these regimes is proposed. The dependence of accelerated electron energy on laser amplitude is also examined. For the majority of this study, the laser propagates along the axis of the target of carbon nanotubes in a 1D geometry. After the fundamental high-density physics is established, an alternative, 2D scheme of laser acceleration of electrons using carbon nanotubes is considered.

Experiments on a MA-class Dense Plasma Focus (DPF) device have been carried out to investigate changes in neutron production by adding moderate amounts of krypton to a deuterium fill gas. The neutron yield from Z-pinch devices, including DPFs, conventionally scales as the peak current to the fourth power. However, a dramatic drop-off from ∼I4 scaling occurs above 3 MA, which recent modeling [D. T. Offermann et al., Phys. Rev. Lett. 116, 195001 (2016)] attributed to the transition in the predominant neutron production mechanism from beam-target fusion to thermonuclear fusion. Previously, the addition of Kr (and other high-Z) dopants has been shown to enhance beam-target fusion yields at currents below 300 kA, with optimal concentrations at 1%–2% Kr, whereas here we show that the optimal concentration of Kr at the MA level is near 0.1% by volume—elucidating a trend in the optimal Kr doping concentration as a function of the device scale. The neutron time-of-flight data reveal that Kr doping creates shorter and more intense neutron bursts, likely due a tighter but unstable pinch, highlighting a key trade-off for Kr doping.

The dense plasma focus (DPF) can be an intense source of x rays, wherein the insulator sleeve strongly dictates the electrical breakdown, which subsequently affects the formation of a plasma sheath and a collapse phase. Experiments on a 25 kJ DPF (operated at 4.4 kJ) are carried out to demonstrate the influence of insulator surface morphology on the pinch structure, dynamics, and x-ray yield using a Ne fill. Two borosilicate insulators are directly compared, one with a smooth finish and the other machined with four circumferential grooves traversing the perimeter of the exterior insulator surface. Comparisons are made through same-shot imaging diagnostics of the evolving plasma sheath during breakdown, rundown, and at the pinch in addition to the time-resolved measurements of emitted x rays via filtered photodiodes. The presence of structures on the insulator sleeve reduces x-ray production across all fill pressures by a factor of 2.8 ± 2.4 on average and reduces the highest x ray producing shots by a factor of 5.5 ± 1.8. Observations of sheath asymmetry and inhomogeneity at lift-off are observed and correlated with subsequent observations of off-axis radial collapse. Taken together, this suggests that local variations in the insulator surface decrease the spatial uniformity of the sheath, leading to an azimuthally asymmetric focus, reduced electron densities, and, ultimately, degraded x-ray production.