Multiple system atrophy (MSA) is a sporadic, neurodegenerative disorder, clinically characterized by Parkinsonian, autonomic, cerebellar and pyramidal signs. We describe two patients showing different presentations of the same disease. The patient on case 1 presents features of MSA-C or olivopontocerebellar atrophy with the pontine "Cross sign" on brain MRI. The second case reports a patient presenting MSA-P or striatonigral degeneration and the brain MRI shows lenticular nucleus sign alteration. Multiple system atrophy (MSA) is a sporadic, neurodegenerative disorder, characterized by several combinations of parkinsonian, autonomic, cerebellar and pyramidal signs.
Lymphangioleiomyomatosis (LAM) is an uncommon interstitial lung disease that exclusively affects women, usually during their reproductive years. LAM is characterized pathologically by abnormal proliferation of LAM cells in the lungs and in thoracic and retroperitoneal lymphatics. 1 We presented a case of 40-year-old female presented to Department of Pulmonary Medicine, Gauhati Medical College with cough and chest pain for 6 months, which was diagnosed to be pulmonary manifestation of Lymphangioleiomyomatosis in HRCT chest.
BACKGROUNDIn recent years, Computed Tomography (CT) has been found to be extremely useful in the diagnosis and treatment of renal masses. It provides an accurate morphologic picture of the renal mass. The precise contrast resolution makes identification of the characteristic attenuation values possible. Aims and Objectives -To characterise benign vs. malignant renal lesions based on CECT image analysis and to stage wherever possible. MATERIALS AND METHODS60 patients with suspected renal mass underwent CECT in Gauhati Medical College for a period from June 2014 to August 2015; patients who were diagnosed to have renal mass on ultrasound and referred for a CT scan for further evaluation. The images were analysed in unenhanced, corticomedullary, nephrographic and excretory phases after administration of non-ionic intravenous contrast. The lesion detection, enhancement pattern, local invasion and distant metastasis were assessed in pre-and post-contrast studies. RESULTSThere were 45 malignant and 15 benign lesions in our study; the radiological diagnoses of malignant mass was confirmed by histopathology, whereas benign lesions were followed up to confirm their benignity. We had two false positive cases in our study, one was an oncocytoma and another was an angiomyolipoma. MDCT was 100% sensitive, 88.2% specificity and reached an accuracy rate of 96.7%. CONCLUSIONAs a result of the study, the following conclusions can be stated: CT has excellent accuracy in the diagnosis, characterisation and differentiating benign and malignant renal masses and for the characterisation of small renal mass the degree of enhancement on the corticomedullary phase is the most valuable parameter.
Polycythemia is a disease state in which the proportion of blood volume that is occupied by red blood cells increases. It can result in increased density of intracranial blood vessels on non-contrast computed tomography scan. This imaging findings can closely mimic appearance of a contrast enhanced CT scan and those of cerebral venous thrombosis. We are presenting a case of 11-year-old child with Fallot's tetralogy who showed abnormally hyperdense intracranial vessels on NCCT of brain.
Kallmann syndrome (KS) is a genetic disorder characterised by hypogonadotrophic hypogonadism and anosmia or hyposmia. The condition has been noted to be present in families. The MRI findings in KS are characteristic and MRI is a useful adjunct to the diagnosis of KS. We are presenting a case of young boy who was short statured and had anosmia with multiple hormonal deficiencies.
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