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Due to various biological factors, males and females differ in their response to drug treatment. However, there is still a lack of knowledge of the effects resulting from sex-differences in the medical field, primarily due to females' underrepresentation in clinical studies. Considering severe diseases related to the cardiovascular system, which are likely to be perilous, counteracting this lack and emphasizing the need for sex-dependent drug treatment is of high importance. Thus, this research-in-progress paper aims to strengthen the female perspective in drug management by proposing design considerations on IS regarding recommender systems in healthcare to reinforce shared decision-making and person-centered care. The resulting artifact presented will be a reference architecture with a mobile application as the interface to patients and healthcare professionals as well as a data-driven backend to collect and process data on sex specificity in the medical treatment of cardiovascular diseases (CVD).