The skin of Mangosteen fruit (Garcinia mangostana L.) is widely used as traditional medicine, for it contains a lot of xanthone compounds. Today, there are many products from mangosteen pericarp extract being sold on the market, one of which is the preparation of mangosteen pericarp capsules. Determining the total xanthone content in the preparation of mangosteen pericarp capsules (Garcinia mangostana L.) circulating on the market needs to be done to calculate the levels of xanthone that are not included in the preparation label. The results of the analysis with UV-Visible Spectrophotometry obtains the maximum absorption wavelength at 243 nm and the linear regression equation of the calibration curve that is y=0,0568+0,0727x with a value of r=0,9999. Validation of the analysis method showed the results of intraday precision obtained % RSD 0,34%, 0,17%, and 0,16%, interday precision of 0,23%, 0,35%, and 0,16%. The accuracy obtained was mean % recovery 95,55%, limit of detection 0,35 μg/ml and limit of quantitation 1,15 μg/ml. The results of the determination of the total xanthone content in the mangosteen pericarp capsules were 100,8 μg/mg in sample A; 197 μg/mg in sample B; and 50,2 μg/mg in sample C.

Acne is one of the most common skin diseases that occur at all ages, especially in adolescents who are just experiencing puberty. One of the plants that has antibacterial properties is the leaves of suruhan. However untill now not found research of suruhan leaf used as an acne medicine. The aim of this study was to determine the antibacterial activity of suruhan leaf extracts on the growth of Propionibacterium acnes. The method used is disc diffusion by given 5 treatments starting with a concentration of 15%, 20%, 25%, positive control of clindamycin and negative control of aquadest.. The results obtained from leaf extracts were able to inhibit the growth of P. acnes bacteria in various concentrations. Suruhan leaf extracts at a concentration of 25% showed response resistance was greater than other concentrations. The one way Anova SPSS test showed p <0.05 which means that there were differences in the inhibitory concentration of various extracts on the growth of P. acnes that cause acne

Indonesia, khususnya di Kepulauan Riau memiliki kekayaan biota laut yang melimpah. Salah satunya adalah spons yang mengandung berbagai macam metabolit sekunder yang memiliki sifat toksik untuk membunuh sel kanker. Potensi sitotoksik yang dimiliki spons dapat digunakan sebagai sumber obat antikanker baru, mengingat kanker merupakan penyakit dengan tingkat kematian tertinggi didunia. Penelitian ini bertujuan untuk mengetahui potensi senyawa bioaktif antikanker pada ekstrak spons laut di Perairan Natuna, Kepulauan Riau. Metoda yang digunakan untuk skrining awal potensi antikanker adalah metoda BSLT. Hasil yang diperoleh menunjukan bahwa toksisitas ekstrak kasar metanol spons laut natuna mempunyai LC50 sebesar 51,64 ppm dan tergolong sangat toksik . Hal ini mempunyai kontribusi besar terhadap pengembangan sumber daya laut yang spesifik asal Kepulauan Riau, dan dapat dikembangkan lebih lanjut sebagai kandidat obat antikanker unggulan.

Pendahuluan: Pemanis sintetis merupakan suatu zat/bahan yang digunakan untuk menimbulkan rasa manis dengan jumlah kalori yang lebih rendah daripada gula pasir. Salah satu pemanis buatan yang sering digunakan adalah sakarin dan siklamat. Konsumsi sakarin dan siklamat dalam dosis tinggi dapat menyebabkan kanker, dan penyakit lainnya seperti tumor paru, hati, limfa, migraine dan sakit kepala. Tujuan: Penelitian ini bertujuan untuk mengetahui kandungan sakarin dan siklamat pada es doger yang dijual di beberapa lokasi di Kota Batam. Metode: Penelitian ini menggunakan metode eksperimental dengan metode pengambilan sampel yang kebetulan ada atau tersedia saat itu sebanyak 12 sampel dari 12 pedagang es doger. Identifikasi sampel dilakukan secara kualitatif dengan uji pengendapan dan uji reaksi warna. Hasil: Hasil uji menunjukkan bahwa sebanyak 12 sampel dari 12 pedagang di beberapa lokasi di  Kota Batam tidak mengandung sakarin dan siklamat. Kesimpulan: Es doger yang dijual di Kota Batam tidak mengandung pemanis buatan.

Objective: Natuna sponge is a marine animal that contains a wide range of secondary metabolites that can be utilized in the field of pharmacy. The research aims to test the phytochemical content and antioxidant activity of the Natuna methanol marine sponge extract. Sample extraction is done by the maceration method with methanol solvent. Methods: Phytochemical tests include alkaloid testing, flavonoids, steroids, saponins, and tannins. Test antioxidant activity using the immersion DPPH method (1.1-diphenyl-2-picryl hydroxyl) measured absorption at a wavelength of 517 nm. Results: The phytochemical test results showing the sponge of Natuna contain secondary metabolites including alkaloids, flavonoids, steroids, saponins, and tannins. Conclusion: This Natuna sponge methanol extract has an antioxidant activity that is very strong with an IC50 value of 52.91 ppm, and the comparator used is Vitamin C with an IC50 value of 43,51 ppm.