What does the term "chronic venous disease" cover? The term "chronic venous disease" (CVD) covers a full spectrum of venous conditions of lower limbs, ranging from patients with early symptoms, like telangiectasia (reticular veins), leg pain, or oedema of the foot, to complications like venous leg ulcers. In the early stages usually only symptoms appear, then as the disease progresses it is accompanied by signs. Venous symptoms are defined as tingling, aching, burning sensation, muscle cramps, swelling, sensations of throbbing or heaviness, itching skin, restless legs, leg tiredness, or fatigue. These may be exacerbated during the course of the day by prolonged standing or by heat, and relieved with leg rest, elevation, or both. Venous signs are visible manifestations of chronic venous disease, which include [1]: • Oedema of the dorsum of foot, the entire foot, possibly extending to the leg; • Frank varicose veins: this may or may not be associated with telangiectasia or reticular veins; • Skin changes: dryness, frank eczema, darkened, thickened, hard, scarred, and ulcers.