Objective. To evaluate the benefits of conditioned medium of Adipose-derived stem cells (ADSC-CM) on wound healing after fractional carbon dioxide laser resurfacing (FxCR) on human skin. Materials and Methods. Nineteen subjects were treated with FxCR on the bilateral inner arms. ADSC-CM was applied on FxCR site of one randomly selected arm. Transepidermal water loss (TEWL), skin color, and gross-elasticity of FxCR site on both arms were measured. Skin samples were taken by biopsy from three subjects 3 weeks after treatment for histopathological manifestations and mRNA expressions of procollagen types I and III, elastin genes were noted. Results. The index of erythema, melanin, and TEWL of the ADSC-CM-treated skin were significantly lower than those of the control side. The mRNA expression of type III procollagen in ADSC-CM-treated group at 3 weeks posttreatment was 2.6 times of that of the control group. Conclusion. Application of allograft ADSC-CM is an effective method for enhancing wound healing after FxCR, by reducing transient adverse effects such as erythema, hyperpigmentation, and increased TEWL.
The requirement of practical high-performance electrolytes is a key bottleneck restricting the development of rechargeable magnesium batteries (RMBs). Electrolytes based on weakly coordinated and fluorinated bulky boron-center anions (B(OR F ) 4 − ) have attracted wide attention for their admirable oxidation stability, high ionic conductivity, and weak corrosion. However, the complex synthesis route and costly raw materials still hinder their wide application. Therefore, a magnesium tetra(trifluoroethanoloxy)borate (Mg[B(Otfe) 4 ] 2 ) is designed not only to inherit these merits above but also greatly cut down the synthetic costs. The as-prepared electrolyte is synthesized by two methods of microcrystal redissolution and in situ reaction, both of them cycle stably for reversible Mg plating−stripping with an average Coulombic efficiency of ∼99% and overpotentials as low as 0.2 V, as well as an oxidation stability of more than 3 V vs Mg at stainless steel. The design strategy of the electrolyte and its compatibility with insertion or replacement-type cathodes promote the realization of practical RMBs.
Organic
redox-active molecules have been identified as promising
cathodes for practical usage of potassium-ion batteries (PIBs) but
still struggle with serious dissolution problems and sluggish kinetic
properties. Herein, we propose a pseudocapacitance-dominated novel
insoluble carbonyl-based cathode, [2,6-di[1-(perylene-3,4,9,10-tetracarboxydiimide)]anthraquinone,
AQ–diPTCDI], which possesses high reversible capacities of
150 mAh g–1, excellent cycle stability with capacity
retention of 88% over 2000 cycles, and fast kinetic properties. The
strong intermolecular interactions of AQ–diPTCDI and in situ formed cathode electrolyte interphase films support
it against the dissolution problem. The high capacitive-like contribution
in capacities and fast potassium-ion diffusion enhance its reaction
kinetics. Moreover, a symmetric organic potassium-ion battery (OPIB)
based on AQ–diPTCDI electrodes also exhibits outstanding K-storage
capability. These results suggest that AQ–diPTCDI is a promising
organic cathode for OPIBs and provide a practicable route to realize
high-performance K storage.
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