Indonesia is a country rich in biodiversity.  Of several plants that can be used as alternative medicine to treat disease.  The efficacy of plants as medicine in health is related to plants having chemical compounds which are the result of secondary metabolites contained in these plants.  One of the secondary metabolites in plants is coumarin.  Coumarins can be found in almost all plants from roots, stems, leaves, flowers and fruit.  The purpose of this study was to isolate and identify coumarin compounds contained in these plants.  In the process of isolating coumarin compounds that can be done by several methods including extraction, phytochemical screening, fractionation, isolation of coumarins and identification of isolates.  Plants containing coumarin compounds that were used in the isolation of coumarins that we reviewed were sundai lime peel (Citrus nobilis Lour), rambutan fruit seeds (Nephelium lappaceum L), water henna leaves (Impatiens Balsemina Linn), harp bark (Sandoricum koetjape) and Artemisia annua L.

Paracetamol (acetaminophen) merupakan obat yang memiliki efek analgesic-antipirek. Telah dilakukan penelitian dengan tujuan untuk menganalisis senyawa parasetamol (acetaminophen) pada urin dengan cara kualitatif menggunakan Gas Chrotography-Mass Spectrometry (CG-MS) dan LC-MS (Liquid Chromathography-Mass Spectrometry). Sampel urin diperoleh dari pasien yang mengkonsumsi paraceramol tanpa mengubah pola konsumsi. Hasil analisis penelitian menunjukan bahwa hasil positif acetaminophen-TMS diperoleh pada sampel urin dari 1 jam hingga sehari setelah mengkonsumsi tablet parasetamol namun diperoleh hasil negative setelah lebih dari 1 hari mengkonsumsi tablet.

Indonesia is a country rich in biodiversity.  Of several plants that can be used as alternative medicine to treat disease.  The efficacy of plants as medicine in health is related to plants having chemical compounds which are the result of secondary metabolites contained in these plants.  One of the secondary metabolites in plants is coumarin.  Coumarins can be found in almost all plants from roots, stems, leaves, flowers and fruit.  The purpose of this study was to isolate and identify coumarin compounds contained in these plants.  In the process of isolating coumarin compounds that can be done by several methods including extraction, phytochemical screening, fractionation, isolation of coumarins and identification of isolates.  Plants containing coumarin compounds that were used in the isolation of coumarins that we reviewed were sundai lime peel (Citrus nobilis Lour), rambutan fruit seeds (Nephelium lappaceum L), water henna leaves (Impatiens Balsemina Linn), harp bark (Sandoricum koetjape) and Artemisia annua L.