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nervous system as a whole, and in particular on the CNS. During cerebral development, vitamin D may act like a neurosteroid hormone in the areas of neurotrans mission, neuroprotection, and neuroimmunomodulation. Moreover, vitamin D deficiency has been associated with neurological and psychiatric disorders. In older adults, hypovitaminosis D has been associated with neuromuscular disorders, dementia, and Parkinson's disease. Thus, vitamin D supplementation might have a protective effect against these neurological disorders. Conclusions: Vitamin D has been associated with many neurological functions and its deficiency with dysfunction. Low serum 25-hydroxyvitamin D concentrations can potentially be reversed. This simple and low-cost correction might contribute to the primo-secondary prevention of various neuropsychiatric disorders.

One of the most exciting issues in psychology is, What are the psychological mechanisms underlying human tool use? The computational approach assumes that the use of a tool (e.g., a hammer) requires the extraction of sensory information about object properties (heavy, rigid), which can then be translated into appropriate motor outputs (grasping, hammering). The ecological approach suggests that humans perceive not the properties of tools per se but what they afford (a heavy, rigid object affords pounding). This is the theory of affordances. In this article, we examine the potential of the computational view and the ecological view to account for human tool use. To anticipate our conclusions, neither of these approaches is likely to be satisfactory, notably because of their incapacity to resolve the issue of why humans spontaneously use tools. In response, we offer an original theoretical framework based on the idea that affordance perception and technical reasoning work together in a dialectical way. The thesis we defend here is that humans have the ability to view body action as a problem to be solved. It is precisely at this point that technical reasoning occurs. However, even if the ability to do technical reasoning gives humans the illusion of constantly doing less (e.g., TV remote control), they are still forced to use body action-and to perceive affordances-to operate the product of the reasoning (pushing buttons with the fingers). This is the principle of dialectic.

Depressed patients showed inability to inhibit neutral information access to working memory, restrain and delete irrelevant information. This impairment in cognitive inhibition could underlie cognitive slowness and attentional deficits in depression.

It has been suggested that gesture engrams, conceptual knowledge and/or the ability to infer function from structure can support object use. The present paper proposes an alternative view which is based upon the idea that object use requires solely the ability to reason about technical means provided by objects. Technical means are abstract principles which are not linked with any object representation (e.g., cutting involves the opposition between dense and permeable material). The technical reasoning model predicts that the inability to perform technical reasoning should impair performance in any situation requiring the use of objects (in a conventional way or not). Twenty left brain-damaged (LBD) patients, 11 right brain-damaged (RBD) patients and 41 healthy controls were examined on experimental tests assessing the conventional use of objects (e.g., screwing a screw with a screwdriver), conceptual knowledge about object function, pantomime of object use and recognition of object utilization gestures. We also designed the Unusual Use of Objects Test, which demands unusual applications of objects to achieve a purpose for which the usually applied object is not provided (e.g., screwing a screw with a knife). The key findings are that only LBD patients have more difficulties on the Unusual Use of Objects Test than controls or RBD patients, and that the severity of their impairment is correlated with that on conventional use of objects. Correlations with tests assessing conceptual knowledge as well as with tests of pantomime of object use and recognition of object utilization gestures were weaker. These results support the technical reasoning model and question the role of conceptual knowledge and gesture engrams in object use. Since the technical reasoning model also predicts two distinct technical disorders, the discussion focuses on the existence of these disorders in regard to individual performance profiles obtained in the Unusual Use of Objects Test.